Extended use of the Mastersizer 2000 at Hexal Pharmaceuticals
In the past year, Mastersizer 2000 systems have been installed at three Hexal sites: at Salutas GmbH, one of the most modern pharmaceutical production sites in Europe, manufacturing more than 5 million tablets and capsules every year; at HEXAL Syntech GmbH, near Dresden, for use in controlling the synthesis of active substances; and at JENAHEXAL Pharma GmbH, the site of Hexal's sterile production. At JENAHEXAL, more than 450 different sterile dosage forms, including injectables, infusions and implants, are produced under GMP cleanroom conditions.
The Mastersizer 2000 is a laser diffraction-based particle size analyzer which measures particle size over an extremely broad range from 0.02 to 2000 microns. Its software-driven Standard Operating Procedures (SOPs) are designed to simplify method development, allow global method transfer and ensure that minimal operator intervention is required during measurements. A SOP-assistant supports the user during the set up of an optimum measurement method, and SOPs can be transferred from instrument to instrument by email - an important feature for global operations.
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