Cost-efficient purification of natural compounds

Gilson International B.V. Deutschland

Slica-free alternative to traditional HPLC columns for extraction, also from crude extracts

Chromatographic purification of natural compounds presents many challenges to scientists because of the complex nature of the starting matrices that are used in the process.
These starting materials can damage traditional columns and cartridges, decreasing the length of their usage and increasing costs; that is, if the particular system can even accommodate the starting material.
Centrifugal partition chromatography (CPC), which uses both liquid stationary and mobile phases, can handle heavily contaminated, complex starting materials, such as direct extracts from many biological sources, and has been shown useful for the isolation of piperine from Pipernigrum, gingerol from ginger and hundreds of other natural compounds from plants.
Additionally, by relying on a liquid stationary phase, CPC columns do not need to be replaced like traditional columns and cartridges used by preparative HPLC and flash chromatography methods.

This article will discuss the basic principles behind CPC and explore the use and benefits of CPC in the purification of cannabinoids from crude cannabis oil.

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Cost-efficient purification of natural compounds

Slica-free alternative to traditional HPLC columns for extraction, also from crude extracts

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Topic world HPLC

HPLC is a key technology in modern analytical chemistry. It enables the separation, identification and quantification of components in complex mixtures with high precision and efficiency. Whether in the analysis of active pharmaceutical ingredients, the quality control of foodstuffs or the examination of biological samples - HPLC is often the method of choice for demanding separation tasks.

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View topic world
Topic world HPLC

Topic world HPLC

HPLC is a key technology in modern analytical chemistry. It enables the separation, identification and quantification of components in complex mixtures with high precision and efficiency. Whether in the analysis of active pharmaceutical ingredients, the quality control of foodstuffs or the examination of biological samples - HPLC is often the method of choice for demanding separation tasks.

20+ products
5+ whitepaper
15+ brochures

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

70+ products
20+ whitepaper
60+ brochures
View topic world
Topic World Chromatography

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

70+ products
20+ whitepaper
60+ brochures