Where do toxins from tobacco attack DNA?

In the future, this could make it easier than ever to determine the safety of many chemical substances

24-Feb-2023 - It is known that toxins in tobacco smoke can change our DNA – but where exactly in the genome they do this has been a mystery. A new approach developed by researchers at ETH Zurich now brings light into the darkness. In the future, this could make it easier than ever to determine the safety of ...

Animal-free safety testing of novel medicines, chemicals, and consumer products

Spin-off from the Leiden University Medical Center opens US office and production facility to accelerate growth

21-Mar-2022 - Toxys BV, a Dutch biotech company that offers a broad spectrum of innovative in vitro toxicology solutions for the safety assessment of novel medicines, (agro)chemicals, cosmetics, and food ingredients, announces the opening of a sales office in New York (NY) and a production facility in ...

Green chemistry needs more green toxicology

Sustainable bioeconomy: Development of environmentally friendly bio-shampoos and plant protection agent technologies

16-Feb-2022 - With the early assessment of sustainable, newly developed chemicals and products it is possible to assess a potential risk of toxic substances being released at a later point in product cascades. This has been revealed in a proof-of-concept study jointly coordinated by Goethe University Frankfurt ...

Do chemicals make you fat?

The EU research project EDCMET is investigating the effect of endocrine disruptors on metabolism

28-Jan-2019 - January 2019 saw the launch of the EU research project EDCMET, in which scientists from the German Federal Institute for Risk Assessment (BfR) are also involved. EDCMET stands for "Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome path-ways" and is ...

ECETOC Task Force provides new insights

Toxicity testing of microparticles and poorly soluble liquids in the water environment

15-Jan-2019 - A Task Force set up by the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has provided new insights into scientific testing for the impact of undissolved particles in the aquatic environment. ECETOC launched the Task Force in response to increasing concerns among the ...

Toxicity of carbon and silicon nanotubes and carbon nanofibers

20-Jul-2018 - Nanoparticles with a wide range of applying, including medicine, damage cells of microalgae Heterosigma akashivo badly. This algae species is widely spread in the Russian Far East marine area. The acute toxic effect exhibited at concentrations of 100 mg/l of carbon nanotubes (CNTs) and silicon ...

Computers outperform lab rats in detecting toxic chemicals

19-Feb-2018 - UL, the science safety company, and Johns Hopkins University have embarked on joint research that has resulted in findings that Artificial Intelligence (AI) is superior in finding toxic substances to traditional animal testing. Beyond being more effective, UL's Cheminformatics REACHAcross™ ...

Cheap and simple detection of neurotoxic chemicals

02-Aug-2017 - There is a limited amount of data on the global health impacts of pesticides, but many injuries and deaths worldwide can be attributed to their misuse. Pesticide contamination of food and water sources is a very serious problem, particularly in third world countries. The detection of these ...

Fluorescence method detects mercury contamination in fish

24-Feb-2017 - Researchers from the University of Burgos (Spain) have developed a fluorescent polymer that lights up in contact with mercury that may be present in fish. High levels of the metal were detected in samples of swordfish and tuna. According to the conclusions of another Spanish study, mercury ...

Synthetic chemicals: Ignored agents of global change

25-Jan-2017 - Despite a steady rise in the manufacture and release of synthetic chemicals, research on the ecological effects of pharmaceuticals, pesticides, and industrial chemicals is severely lacking. This blind spot undermines efforts to address global change and achieve sustainability goals. So reports a ...