Synthesis - 21 News from the science department by Universität Münster

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Synthesis - 21 News from the science department by Universität Münster

Tip: You can further refine your news selection by industries.

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New method for producing innovative 3D molecules

Research team synthesises three-dimensional ring structures as potential alternatives to biologically active flat rings

25-Oct-2024 - As its name suggests, ring-shaped “cage molecules” resemble a cage, and it is this three-dimensional structure that makes them significantly more stable than related, flat molecules. Consequently, they could be of interest to drug developers as they represent a possible alternative to ...

synthesis bicyclobutane drug design
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Chemists mimic natural molecular structures: New possibility for vaccine development

Fluorinated sugar molecules as vaccine leads against meningitis B and C

28-May-2024 - Meningococci (Neisseria meningitidis) are disease-causing bacteria that cause life-threatening meningitis, or blood poisoning (septicaemia). There are a number of meningococcal variants worldwide, known as serogroups, and in Germany the Standing Committee on Vaccination (STIKO) recommends ...

synthesis artificial molecules blood poisoning
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New method for introducing fluorinated components into molecules

Chemists have developed a synthesis method for the site-selective integration of the biologically relevant difluoromethyl group into pyridines

21-May-2024 - The difluoromethyl group often determines the properties of bioactive molecules and is therefore particularly interesting for drug research. This atomic group consists of carbon, two fluorine atoms and a hydrogen atom. Derivatives of the chemical compound pyridine are particularly suited for ...

synthesis agrochemicals agrochemistry
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New computer-aided strategy for assessing the applicability of chemical reactions

Counteracting subjective bias in studies on the production of new chemical compounds

12-Apr-2024 - Chemists often develop and optimise new chemical reactions using so-called model systems, i.e. simple, easily accessible substrates. They then use up to around 100 other substrates as examples to show that the reaction works. This demonstration of versatile applicability is called “scope” in ...

synthesis chemical reactions machine learning
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Chemical synthesis: new strategy for skeletal editing on pyridines

Chemists realised “chemical surgery” on ring-shaped compounds

25-Jan-2024 - In the field of chemistry, so-called skeletal editing is seen as a method suitable for changing ring-shaped structures precisely by swapping individual atoms. A team of researchers led by Prof. Armido Studer from the Institute of Organic Chemistry at the University of Münster has now introduced a ...

synthesis functional groups pyridine
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Chemists present method for the fluorination of enines

The new synthesis method produces a wide range of difluorinated molecular building blocks that can be candidates for new active substances

23-Oct-2023 - Fluorinated small molecules are very often used to produce medicines or agrochemicals. However, they rarely occur naturally. The societal importance of fluorinated substances, combined with the lack of natural sources, has created a demand for effective, sustainable methods to generate new ...

synthesis fluorinated compounds Fluorination
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Chemists develop reaction cascade to produce fluorinated molecules

"Molecular origami" creates new structures in a single operation

14-Jul-2023 - Fluorine is found rarely in naturally occurring organic molecules. However, this chemical element is indispensable for the production of pharmaceuticals or agrochemicals. Synthetic chemistry has an important role to play in the development of new fluorine-containing molecular fragments. Simple, ...

synthesis Fluorination fluorine
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Light as a tool for the synthesis of complex molecules

Chemists at the University of Münster have developed a novel and straightforward way to produce complex organic molecules

05-Aug-2022 - Chemists at the University of Münster have developed a novel and straightforward way to produce complex organic molecules. Mild reaction conditions, simple operation, scalability and the use of an inexpensive and commercially available photosensitizer make the method interesting for industrial ...

synthesis beta amino acids oxime oxalate ester
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Chemists develop new multi-component reaction

More environmentally friendly approach produces complex molecular structures in one step: Ketyl radicals "tamed" by photocatalysis

15-Jun-2022 - A more sustainable use of chemical resources is part of the United Nations' Agenda 2030. Synthetic chemists are therefore working to design and carry out efficient syntheses. Within the synthetic organic chemist's arsenal, processes that link several molecules (coupling partners) in a single step ...

synthesis catalysis ketyl radicals
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More Data in Chemistry

Clearer reporting of negative experimental results would improve reaction planning in chemistry

13-Jun-2022 - Databases containing huge amounts of experimental data are available to researchers across a wide variety of chemical disciplines. However, a team of researchers have discovered that the available data is unsuccessful in predicting the yields of new syntheses using artificial intelligence (AI) ...

synthesis chemical synthesis artificial intelligence
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See the theme worlds for related content

Topic world Synthesis

Chemical synthesis is at the heart of modern chemistry and enables the targeted production of molecules with specific properties. By combining starting materials in defined reaction conditions, chemists can create a wide range of compounds, from simple molecules to complex active ingredients.

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4 whitepaper
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Topic world Synthesis

Topic world Synthesis

Chemical synthesis is at the heart of modern chemistry and enables the targeted production of molecules with specific properties. By combining starting materials in defined reaction conditions, chemists can create a wide range of compounds, from simple molecules to complex active ingredients.

15+ products
4 whitepaper
15+ brochures
View topic world
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