Pharmaceutical research - 12 News from the science department for the chemistry industry

Tip: You can further refine your news selection by organizations and countries.

Pharmaceutical research - 12 News from the science department for the chemistry industry

Tip: You can further refine your news selection by organizations and countries.

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New method for introducing fluorinated components into molecules

Chemists have developed a synthesis method for the site-selective integration of the biologically relevant difluoromethyl group into pyridines

21-May-2024 - The difluoromethyl group often determines the properties of bioactive molecules and is therefore particularly interesting for drug research. This atomic group consists of carbon, two fluorine atoms and a hydrogen atom. Derivatives of the chemical compound pyridine are particularly suited for ...

pharmaceutical research agrochemicals agrochemistry
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Electrochemistry Paves the Way: Sustainable Synthesis Method Reveals N-Hydroxy Modifications for Pharmaceuticals

Closing knowledge gaps - new findings on heterocycles

18-Apr-2024 - New highly selective and scalable electro-organic synthesis of novel benzo[e]-1,2,4-thiadiazine-1,1-dioxides which represent an important structural motif of APIs (active pharmaceutical ingredients) modified with a unique N-hydroxy moiety. Recently published research results enable preparative ...

pharmaceutical research drug design electrochemistry
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How scientists are accelerating chemistry discoveries with automation

New statistical-modeling workflow may help advance drug discovery and synthetic chemistry

12-Apr-2024 - A new automated workflow developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has the potential to allow researchers to analyze the products of their reaction experiments in real time, a key capability needed for future automated chemical processes. The developed ...

pharmaceutical research automation chemical reactions
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Click, click, boom—150 new molecules within days instead of months

A new study calls accelerated SuFEx click chemistry “a robust platform for drug discovery”

08-Apr-2024 - Cold Spring Harbor Laboratory (CSHL) chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show promise for development as antibiotics and cancer therapies. Sounds like a ...

pharmaceutical research antibiotics cancer
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Artificial intelligence: Unexpected results

Cheminformatics take a look behind the scenes of machine learning in drug research

15-Nov-2023 - Artificial intelligence (AI) is on the rise. Until now, AI applications generally have “black box” character: How AI arrives at its results remains hidden. Prof. Dr. Jürgen Bajorath, a cheminformatics scientist at the University of Bonn, and his team have developed a method that reveals how ...

pharmaceutical research artificial intelligence machine learning
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Device 'smells' seawater to discover, detect novel molecules

Promising for drug discovery in fragile ecosystems, including coral reefs

10-Nov-2023 - Under the ocean’s surface, marine organisms are constantly releasing invisible molecules. Some of the chemical clues reveal which creatures are nearby, while others could be used someday as medications. Now, researchers in ACS Central Science report a proof-of-concept device that “sniffs” ...

pharmaceutical research drug design marine chemistry
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Breathing new life into tired drugs and agrochemicals

‘Chemical cube’ tools for building new drugs and agrochemicals

04-Apr-2023 - In an ongoing discovery program, a chemical-creation platform is being unearthed – based on cubic molecules – that could help breathe new life into tired drugs and agrochemicals. The University of Queensland’sProfessor Craig Williamssaid the platform, developed in collaboration with CSIRO, is ...

pharmaceutical research active ingredient research agrochemicals
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Thanks to artificial intelligence: New method for targeted design of molecules

Potential applications include industrial processes, drug discovery and optoelectronics

09-Feb-2023 - Engineering novel molecules and materials with specific properties can yield significant advances for industrial processes, drug discovery and optoelectronics. However, the search for novel molecules and materials is comparable to looking for a needle in a haystack, since the number of molecules ...

pharmaceutical research active ingredient research artificial intelligence
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The fountain of life: Water droplets hold the secret ingredient for building life

Chemists discover key to early Earth chemistry, which could unlock ways to speed up chemical synthesis for drug discovery

05-Oct-2022 - Purdue University chemists have uncovered a mechanism for peptide-forming reactions to occur in water — something that has puzzled scientists for decades. “This is essentially the chemistry behind the origin of life,” saidGraham Cooks, theHenry Bohn Hass Distinguished Professor of Analytical ...

pharmaceutical research amino acids chemical reactions
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New reaction facilitates drug discovery

Old inspiration, new chemical trick

07-Sep-2022 - Chemists at ETH Zurich have found a facile method that allows a commonly used building block to be directly converted into other types of important compounds. This expands the possibilities of chemical synthesis and facilitates the search for new pharmaceutically active ingredients. Medications ...

pharmaceutical research active ingredient research active ingredient search
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