Chemists develop new approach to inserting single carbon atoms

Skeletal editing employed to enlarge molecule rings

12-Jan-2024 - Molecules with a central ring system play an important role in the search for active ingredients for new pharmaceutical products – and it is important that the rings should have the correct size if the desired product is to be manufactured as efficiently as possible. For this purpose, an ...

Chemists develop new process for the production of ring-shaped molecules

Photocatalysis as the key

11-Jul-2023 - Most drugs on the market consist of cyclic (ring-shaped) molecules, many of which contain multiple rings. Developing simple and powerful methods for constructing important and novel ring systems remains a task and challenge for chemists in order to produce drugs more efficiently and also to ...

Chemists discover new reactivity of strained molecules

Light energy enables the reaction of double bonds with strained single bonds to produce three-dimensional molecules

24-Mar-2022 - In synthetic organic chemistry, so-called cycloadditions are a particularly important class of reactions. With this type of reaction, ring-shaped molecules can be constructed simply and efficiently by joining (“adding“) two compounds that each contain double bonds. A team led by Prof. Dr. Frank ...

Triggered by light, a novel way to switch on an enzyme

Researchers identify enzyme which becomes catalytically active by light

28-May-2020 - In living cells, enzymes drive biochemical metabolic processes enabling reactions to take place efficiently. It is this very ability which allows them to be used as catalysts in biotechnology, for example to create chemical products such as pharmaceutics. Researchers now identified an enzyme ...

Otto-Roelen Medal for Frank Glorius

Highly innovative and efficient synthesis methods

11-Feb-2020 - Prof. Frank Glorius from Westfälische Wilhelms-Universität Münster / Germany receives the Otto-Roelen Medal 2020. This prize will be awarded by DECHEMA and the German Catalysis Society in recognition of his developments in the field of chemo- and stereoselective hydrogenation of aromatics. The ...

New synthesis method for producing fluorinated piperidines

23-Jan-2019 - A team of chemists at the University of Münster led by Prof. Frank Glorius have developed a new, simple synthetic method for producing fluorinated piperidines –which had previously been very difficult. These compounds play a major role in the development of new active ingredients. Synthetic ...

Chemists present new reaction path

Symmetrical cleavage of disulphides is fast and biocompatible

08-Aug-2018 - A team of researchers led by Prof. Frank Glorius and Michael Teders from the University of Münster and by Prof. Dirk Guldi from the University of Erlangen-Nuremberg have presented a new chemical reaction path which may prove to be of interest both for research and for the production of active ...

Inspired by the chemistry of the eye: Research team develops innovative catalytic chemistry process

04-Sep-2015 - Nature can do it, and chemists in the lab often dream of doing it: producing substances simply and ecologically – as far as possible without any undesirable side-products. A team of researchers from Münster University has now succeeded in turning to its advantage a chemical reaction which takes ...