Novel synthesis of fluorinated molecules with potential in drug research developed

The new synthetic method relies on two fundamentally challenging chemical processes

25-Jun-2024 - A research team from Kiel has described a method for directly converting carbon-hydrogen bonds in carboxylic acids into carbon-fluorine bonds. Carboxylic acids are one of the most important substance classes in chemistry and are a component of many drugs such as aspirin and ibuprofen. To tailor ...

Using computer game technology to develop new materials and new active substances against diseases

Bringing molecular relationships to the big screen of virtual reality

16-Nov-2023 - Bio-chemical research is increasingly dependent on accurate computer modeling and analysis. This requires different disciplines such as natural sciences, computer science and engineering to work hand in hand. A research group has been established at Bonn-Rhein-Sieg University of Applied Sciences ...

Breathing new life into tired drugs and agrochemicals

‘Chemical cube’ tools for building new drugs and agrochemicals

04-Apr-2023 - In an ongoing discovery program, a chemical-creation platform is being unearthed – based on cubic molecules – that could help breathe new life into tired drugs and agrochemicals. The University of Queensland’sProfessor Craig Williamssaid the platform, developed in collaboration with CSIRO, is ...

Thanks to artificial intelligence: New method for targeted design of molecules

Potential applications include industrial processes, drug discovery and optoelectronics

09-Feb-2023 - Engineering novel molecules and materials with specific properties can yield significant advances for industrial processes, drug discovery and optoelectronics. However, the search for novel molecules and materials is comparable to looking for a needle in a haystack, since the number of molecules ...

New reaction facilitates drug discovery

Old inspiration, new chemical trick

07-Sep-2022 - Chemists at ETH Zurich have found a facile method that allows a commonly used building block to be directly converted into other types of important compounds. This expands the possibilities of chemical synthesis and facilitates the search for new pharmaceutically active ingredients. Medications ...

AI learns the language of chemistry to predict how to make medicines

05-Sep-2019 - University of Cambridge researchers have shown that an algorithm can predict the outcomes of complex chemical reactions with over 90% accuracy, outperforming trained chemists. The algorithm also shows chemists how to make target compounds, providing the chemical 'map' to the desired ...

SMART: Facial recognition for molecular structures

Paradigm shift in interpretation of NMR spectra

09-Nov-2017 - An interdisciplinary team of researchers at the University of California San Diego has developed a method to identify the molecular structures of natural products that is significantly faster and more accurate than existing methods. The method works like facial recognition for molecular ...