Chemoselective reduction with non-flammable gold catalyst
Yong Cao / Fudan University
Traditionally this transformation relies on the use of homogeneous transition metal complexes, which are not very practical, Cao explains. Although several heterogeneous catalysts have been reported (which can be separated and reused) they are generally not as active as the homogeneous catalysts, and are either flammable or moisture-sensitive. Therefore an efficient heterogeneous catalyst for transfer reduction, that can be easily handled or stored under ambient conditions, is very desirable.
This supported gold catalyst is highly efficient and chemoselective for the reduction of carbonyl and nitro groups under transfer hydrogenation conditions. Cao and colleagues conducted five successive runs without any drop in the reaction rate, demonstrating the efficiency and stability of the new catalyst.
Original publication: Yong Cao et al., Chem. Commun., 2008
Organizations
Other news from the department science
Get the chemical industry in your inbox
From now on, don't miss a thing: Our newsletter for the chemical industry, analytics, lab technology and process engineering brings you up to date every Tuesday and Thursday. The latest industry news, product highlights and innovations - compact and easy to understand in your inbox. Researched by us so you don't have to.