Thermo Fisher Scientific Offers Unique LC-MS/MS Offering with Cohesive Technologies Acquisition

31-Jan-2007

Thermo Fisher Scientific Inc. announced the acquisition of Cohesive Technologies Inc, a manufacturer of advanced sample extraction and high performance liquid chromatography products. The newly acquired technology shall enhance the existing Thermo Scientific liquid chromatography (LC) and mass spectrometry (MS) product portfolio by minimizing sample preparation in LC, especially for drug discovery, drug development and clinical research applications. According to the company, this unique solution allows scientists to reduce matrix effects during pre-clinical bioanalysis, making it easier to comply with the FDA/CDER Bioanalytical method validation Guidance that states that "In the case of LC-MS-MS-based procedures, appropriate steps should be taken to ensure the lack of matrix effects throughout the application of the method, especially if the nature of the matrix changes from the matrix used during method validation."

The technology works by retaining small molecules, filtering out proteins and larger materials by diffusion, size exclusion and column chemistry. This enables users to directly inject biological samples into the LC-MS/MS system prior to analysis, a significant advantage in pre-clinical bioanalysis, where extensive sample preparation is too time-consuming due to the high sample loads.

Other news from the department business & finance

Most read news

More news from our other portals

All FT-IR spectrometer manufacturers at a glance

See the theme worlds for related content

Topic World Mass Spectrometry

Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!

35+ products
5+ whitepaper
30+ brochures
View topic world
Topic World Mass Spectrometry

Topic World Mass Spectrometry

Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!

35+ products
5+ whitepaper
30+ brochures

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

70+ products
20+ whitepaper
60+ brochures
View topic world
Topic World Chromatography

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

70+ products
20+ whitepaper
60+ brochures