Tularik Receives Milestone Payment From Eli Lilly And Company
As part of the July 2001 acquisition of the computer-aided molecular design (CAMD) unit of Protherics PLC, Tularik inherited all existing CAMD research agreements, including the anti-thrombotic research collaboration with Lilly. In addition, the acquisition included proprietary virtual screening and molecular modeling software and a team of software designers, computational chemists and medicinal chemists.
The multi-year Lilly collaboration was established to design and optimize inhibitors of Factor Xa using Tularik’s CAMD technology, as well as to investigate other potential anti-thrombotic targets. In addition to the current milestone payment, Tularik is entitled to additional payments for Factor Xa inhibitors as they progress through clinical trials to registration. Royalties are payable on sales of products emerging from the collaboration.
"The use of these capabilities in a successful collaboration with Lilly further demonstrates the value of our new, proprietary CAMD technology," remarked David V. Goeddel, Ph.D., Tularik’s CEO. "The acquisition of virtual screening capabilities is another example of Tularik’s strategy to apply novel technologies to augment and accelerate our small molecule drug discovery effort."
Factor Xa inhibitors are a new class of compounds targeting the blood-clotting process, with the aim of preventing or limiting clot formation. Blood clots cause serious and often fatal conditions, including heart attacks, strokes and deep vein thrombosis. Current therapies for these diseases rely mainly on injectable drugs, which have drawbacks in clinical usage. Over 10 million people worldwide are eligible to receive oral anticoagulants for the prevention and treatment of thrombotic diseases.
Most read news
Other news from the department business & finance
These products might interest you
Limsophy by AAC Infotray
Optimise your laboratory processes with Limsophy LIMS
Seamless integration and process optimisation in laboratory data management
ERP-Software GUS-OS Suite by GUS
Holistic ERP solution for companies in the process industry
Integrate all departments for seamless collaboration
LAUDA.LIVE by LAUDA
LAUDA.LIVE - The digital platform for your device management
Comprehensive fleet management options for every LAUDA device - with and without IoT connectivity
ZEISS ZEN core by Carl Zeiss
ZEISS ZEN core - Your Software suite for connected microscopy in laboratory and production
The comprehensive solution for imaging, segmentation, data storage and analysis
ACD Spectrus Platform by ACD/Labs
Software for Analytical Data Handling in R&D
Standardized Analytical Data Processing & Knowledge Management
Get the chemical industry in your inbox
From now on, don't miss a thing: Our newsletter for the chemical industry, analytics, lab technology and process engineering brings you up to date every Tuesday and Thursday. The latest industry news, product highlights and innovations - compact and easy to understand in your inbox. Researched by us so you don't have to.