Sigma-Genosys and Compugen Introduce Genome Libraries For High Throughput Analysis of Gene Function

26-Oct-2001

Sigma-Genosys, a member of the Sigma-Aldrich family (NASDAQ:SIAL), and Compugen (NASDAQ:CGEN) announced today the commercial launch of OligoLibraries(TM), co-branded genome oligonucleotide collections for gene expression profiling, at the 13th International genome sequencing and Analysis Conference (GSAC) in San Diego.

In June 2001, the two companies announced an alliance for the design, manufacture and commercialization of three designated OligoLibraries representing the mouse, rat and human genome. Compugen leverages its LEADS(TM) platform and DNA Chip Design Services to address redundancy, incorporate alternative splicing and consider specificity and cross-homology while developing content and designs for the genome collections. Sigma-Genosys manufactures the products using its patented Abacus(TM) oligo synthesis platform and technologies. The products are co-marketed by both parties under a revenue sharing agreement. Customers of the OligoLibraries will be able to access certain gene sequences and other information relating to OligoLibraries through Compugen's LabOnWeb (www.labonweb.com) life science Internet research engine.

These genome libraries have been available under a limited early access program within Johns Hopkins University, the Medical Research Council, UK, the National Institutes of Health, National University of Singapore, National Cancer Institute's Advanced Technology Center at Gaithersburg, Maryland and the University of North Carolina.

The public launch of OligoLibraries now provides the life sciences research community with access to oligonucleotide collections for high throughput gene expression analysis, drug discovery and functional assays.

"These new oligonucleotide collections, utilizing Sigma-Genosys' expertise in long oligo production and Compugen's superior computational biology, provide the researcher with a more accurate and informative look at the human, mouse and rat genomes," said David Julien, President of the Biotechnology division of Sigma-Aldrich.

"Our collaboration with a market leader such as Sigma-Aldrich allows us to deliver the highest understanding of the human, mouse and rat genomes for the analysis of gene function. Together we are able to offer a high-quality manufacturing process combined with data precision and design accuracy, creating the best product currently available," said Mor Amitai, Ph.D., President and Chief Executive Officer of Compugen. "We are encouraged by the early market enthusiasm and have received positive feedback from initial results obtained by several early access customers," he added.

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