LION bioscience Enters Cheminformatics Market with LeadNavigator(TM)

25-Aug-2004

LION bioscience announced the launch and immediate availability of LeadNavigator(TM), a chemically intelligent analytics product that enables research organizations to make faster and better compound identification, optimization and prioritization decisions. The new cheminformatics product allows researchers to analyze large sets of chemical and numerical data through a single, intuitive interface, which enables more efficient decision-making and collaboration by an organization without adding unnecessary complexity and overhead. LeadNavigator(TM) is a component of LION Lead Engine, LION's cheminformatics product suite.

LeadNavigator(TM) leverages the technology developed by LION as part of the Bayer PIx (Pharmacophore Informatics) project. "The PIx project was initiated in 2000 to improve Bayer's ability to identify, select and optimize the most promising drug candidates, by pulling together and visualizing data from several diverse sources. While regular chemical spreadsheets can partly solve this problem, the available solutions have not been well adapted for medicinal chemistry. Commercially available software has had limited chemical intelligence, forcing scientists to go back and forth between their data and their analysis tools, wasting valuable time," said Hanno Wild, Ph.D., Head of Medicinal Chemistry at Bayer HealthCare AG. "The chemical worksheet is the central component of the PIx platform, and it is currently being used at Bayer by scientists worldwide. Through the chemical spreadsheet LION developed for us, Bayer scientists have access to all relevant data and tools from a single point of access. LION's decision to productize this proven technology in LeadNavigator(TM) will be beneficial to the life science industry."

"During the compound optimization stage of the discovery cycle, researchers are interested in not only figuring out the key structural features responsible for activity and selectivity, but also what structural changes need to be made to improve these characteristics," said Joseph F. Donahue, LION's Chief Business Officer and North American President. "In order to address these questions, a variety of search and analysis methodologies, along with visualization tools for structural and numerical data, are routinely deployed throughout an organization. As with biological data, chemical information is located in many different databases, with different interfaces, making it very frustrating to effectively use and make decisions from all of the available data. LeadNavigator(TM) provides easy access to all of these tools and data, through one interactive interface, which combines spreadsheet functionality and advanced data visualization capabilities with both standard statistical calculations and analyses methods specific to chemical compound selection."

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