Chenomx, Inc. and Varian, Inc. Form Distribution Relationship For 'Eclipse' Metabolite-Profiling Software

24-Sep-2003

Varian, Inc. and Chenomx, Inc., a leader in the rapidly growing field of metabolic profiling, announced that they have entered into a distribution agreement to market Chenomx's "Eclipse" bioprofiling software, which can be used with data acquired from Varian, Inc. 400 MHz - 700 MHz NMR spectrometers.

Metabolic profiling, or metabonomics, is the study of low molecular weight chemicals, known as metabolites, found in a living organism. Metabolite levels can differ due to a variety of effects, such as drug ingestion, hence metabolic profiling is used to evaluate the efficacy or toxicity of drug candidates, helping researchers develop safer and more effective pharmaceuticals. NMR data can be particularly informative, as the metabolites in a bio-fluid sample can be viewed and quantified with just one experiment. When this information is gathered from a number of samples, it can be used to generate a series of metabolic profiles that correspond to different drugs, diseases or other causes of biochemical change.

Chenomx's "Eclipse" software uses proprietary mathematical algorithms to separate the individual metabolite signals from the mixture of metabolites that occur in urine or blood. It then analyzes the separate components using sophisticated databases. When combined with NMR spectra generated by Varian, Inc. spectrometers, this provides a one-step analysis that can correlate with a drug's efficacy or toxicity. Varian, Inc.'s NMR spectrometers are well-known for their sensitivity and flexibility and are used for a broad number of small molecule and proteomics applications.

Other Varian, Inc. instrumentation, including LC-NMR/MS, UV-Vis, photo diode array, mass spectrometers and NMR spectrometers, can be used with the overall metabolic profiling process to help identify unknown or low concentration compounds within the biofluid. Each individual metabolite found can be added to the existing databases, enhancing the quantitative capability of the Chenomx software.

Other news from the department research and development

These products might interest you

Agera

Agera by HunterLab Europe

Measure color and gloss level simultaneously - in seconds

Easy-to-use colorimeter: standard-compliant, robust and precise

colorimeters
SPECORD PLUS

SPECORD PLUS by Analytik Jena

SPECORD PLUS Series - Maximum precision in UV/Vis

The modern classic guarantees the highest quality

ERASPEC

ERASPEC by eralytics

Spectral Fuel Analysis in Seconds with ERASPEC

Fast delivery of over 40 fuel parameters at the push of a button

ZEEnit

ZEEnit by Analytik Jena

Zeeman Technology for Maximum Sensitivity – Matching any Analytical Problem

Transverse-heated graphite furnace for optimum atomization conditions and high sample throughput

AAS spectrometers
contrAA 800

contrAA 800 by Analytik Jena

contrAA 800 Series – Atomic Absorption. Redefined

The best of classical atomic absorption and ICP-OES spectrometry are combined in the contrAA 800

ICP-OES spectrometer
PlasmaQuant 9100

PlasmaQuant 9100 by Analytik Jena

PlasmaQuant 9100 Series of ICP-OES Instruments

Reveal the Details That Matter

ICP-OES spectrometer
NANOPHOX CS

NANOPHOX CS by Sympatec

Particle size analysis in the nano range: Analyzing high concentrations with ease

Reliable results without time-consuming sample preparation

particle analyzers
NEX CG II

NEX CG II by Applied Rigaku Technologies

Elemental analysis at ppb level for exact results

X-ray fluorescence spectrometers
INVENIO

INVENIO by Bruker

FT-IR spectrometer of the future: INVENIO

Freely upgradeable and configurable FT-IR spectrometer

FTIR spectrometers
ALPHA II

ALPHA II by Bruker

Chemical analysis made easy: compact FT-IR system

Increase the efficiency of your routine analyses with user-friendly technology

FTIR spectrometers
Microspectrometer

Microspectrometer by Hamamatsu Photonics

Ultra-compact microspectrometer for versatile applications

Precise Raman, UV/VIS and NIR measurements in portable devices

microspectrometers
2060 Raman Analyzer

2060 Raman Analyzer by Metrohm

Self-calibrating inline Raman spectrometer

Analyze solids, liquids and gases - for reproducible, accurate results in the process

novAA®  800

novAA® 800 by Analytik Jena

The Analyzer 4 You - novAA 800-Series

The reliable all-rounder, making routine analysis efficient and cost-effective

PlasmaQuant MS Elite

PlasmaQuant MS Elite by Analytik Jena

LC-ICP-MS Is the Key to the World of Elemental Species

Highest Sensitivity and Lowest Detection Limits with PlasmaQuant MS Series and PQ LC

S4 T-STAR

S4 T-STAR by Bruker

TXRF spectrometer: Sub-ppb detection limits & 24/7 analytics

Minimal operating costs because no gases, media or lab equipment are required

total reflection x-ray fluorescence spectrometers
S2 PICOFOX

S2 PICOFOX by Bruker

Fast and precise trace element analysis on the move

TXRF technology for minimal samples and maximum efficiency

total reflection x-ray fluorescence spectrometers
Micro-Z ULS

Micro-Z ULS by Rigaku

Accurately measure sulphur content in fuels: WDXRF analyser

Reliable routine analyses with 0.3 ppm detection limit and compact design

WDXRF spectrometers
ZSX Primus IVi

ZSX Primus IVi by Rigaku

High-precision WDXRF analysis for industrial applications

Maximum sensitivity and throughput for light elements and complex samples

X-ray fluorescence spectrometers
SPECTRO ARCOS

SPECTRO ARCOS by SPECTRO Analytical Instruments

The inductively coupled plasma optical emission spectrometer (ICP-OES) for highest demands

The top-of-line SPECTRO ARCOS ICP-OES analyzer evolves elemental analysis to the next level

ICP-OES spectrometer
BIOS ANALYTIQUE - Soluciones de Renting y Leasing para laboratorios

BIOS ANALYTIQUE - Soluciones de Renting y Leasing para laboratorios by Bios Analytique

Specialists in the rental and leasing of scientific equipment for laboratories throughout Europe

Whether you have an unexpected requirement or limited budget, we have the perfect solution for you

lab equipment
Loading...

Most read news

More news from our other portals

All FT-IR spectrometer manufacturers at a glance

See the theme worlds for related content

Topic World Spectroscopy

Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!

70+ products
40+ whitepaper
60+ brochures
View topic world
Topic World Spectroscopy

Topic World Spectroscopy

Investigation with spectroscopy gives us unique insights into the composition and structure of materials. From UV-Vis spectroscopy to infrared and Raman spectroscopy to fluorescence and atomic absorption spectroscopy, spectroscopy offers us a wide range of analytical techniques to precisely characterize substances. Immerse yourself in the fascinating world of spectroscopy!

70+ products
40+ whitepaper
60+ brochures