Sigma-Genosys Expands Its Relationship with Compugen Ltd.

10-Dec-2002

Sigma-Genosys, a member of the Sigma-Aldrich family, announced the expansion of its relationship with Compugen Ltd. through the launch of three new genome oligonucleotide collections for gene expression profiling. The expanded offerings of Zebrafish and B. subtilis are comprehensive collections that represent approximately 16,000 (zebrafish) and 4,000 (B. subtilis) oligonucleotide probes (65mer) respectively. In addition, an E. coli library will represent the entire K12 genome as well as two sequencings of the pathogenic 0157 strain. These products are manufactured by Sigma-Genosys and designed by Compugen.

Sigma-Genosys continues its commitment to the whole genome oligonucleotide library platform through the addition of new model organisms to its already existing product line of human, mouse and rat libraries as well as the ongoing investment towards automation and upgrading of its proprietary manufacturing technologies and processes. Additionally, the distinct and differentiated value of this offering is driven through Compugen's proprietary LEADS(TM) platform and DNA Chip Design Services to address redundancy, alternative splicing, specificity and cross-homology. The performance and value of the existing platforms is exemplified both by the increasing number of users and generation of scientific data.

"The Sigma-Genosys and Compugen oligonucleotide libraries have assisted us significantly in our analysis of gene function and provided us with a more accurate representation of several genomes. We are using the human collection for a number of different projects, including expression profiling of various cancers and determining host responses to infectious agents; the rat collection is used to study the effect of spinal cord injuries. As a result of the successful contribution of these oligonucleotide libraries to advance our research, we recently purchased an additional collection, that of the Bacillus Subtilis," said Dr. Peter Tolias, Director of the Center for Applied Genomics at the Public Health Research Institute, Newark, NJ.

In June 2001, Sigma-Genosys and Compugen announced an alliance for the design, manufacture and commercialization of oligonucleotide libraries. "Adding these three model organisms to the growing list of oligonucleotide libraries confirms the strong and continuing collaboration between Sigma-Genosys and Compugen," said Cal Froberg, President of Sigma-Genosys. "This partnership leverages the strength of both companies and confirms our commitment to add to the collection of libraries for the life science research community."

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