50 Millionth Unique Chemical Substance Recorded in CAS REGISTRY

Novel analgesic marks major milestone in scientific discovery

09-Sep-2009 - USA

Chemical Abstracts Service (CAS), a division of the American Chemical Society, announced that on September 7i t recorded the 50 millionth substance in CAS REGISTRY. The recently registered substance is a novel arylmethylidene heterocycle with analgesic properties. Reaching the 50 million mark so quickly is an indicator of the accelerating pace of scientific knowledge. CAS registered the 40 millionth substance just nine months ago - in contrast, it took 33 years for CAS to register the 10 millionth compound in 1990.

Information professionals and scientists around the world have taken note of this important milestone." The rapid growth of CAS REGISTRY is a mirror of the breadth and depth of creativity in research labs throughout the world," said Grace Baysinger, head librarian at the Swain Chemistry and Chemical Engineering Library at Stanford University.

The 50 millionth substance (CAS Registry Number 1181081-51-5) was uncovered by CAS scientists from the Examples section of a nearly 200-page patent issued by the World Intellectual Property Organization on August 13, 2009. According to the patent, "Few therapeutics are approved by the US Food and Drug Administration and other regulatory agencies for the treatment of neuropathic pain." To address this concern, a series of novel arylmethylidene heterocycles were synthesized, which included the most recent substance registered by CAS.

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