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Tuaminoheptane



Tuaminoheptane
Systematic (IUPAC) name
heptan-2-amine
Identifiers
CAS number  ?
ATC code R01AA11
PubChem 5603
Chemical data
Formula C7H17N 
Mol. mass 115.217 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?


Tuaminoheptane (or tuamine) is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.[1] However it can cause skin irritation,[2] which limits its usefulness as a nasal decongestant. Side effects can include acute glaucoma, tachycardia and hypertension.[1]



References

  1. ^ Delicado EG, Fideu MD, Miras-Portugal MT, Pourrias B, Aunis D. Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. Biochemical Pharmacology. 1990 Aug 15;40(4):821-5.
  2. ^ Raoux M, Colomban C, Delmas P, Crest M. The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes. Molecular Pharmacology. 2007 Jun;71(6):1685-94.
v • d • e
Decongestants and other nasal preparations (R01)
Topical: sympathomimetics, plainCyclopentamine - Ephedrine - Phenylephrine - Oxymetazoline - Tetryzoline - Xylometazoline - Naphazoline - Tramazoline - Metizoline - Tuaminoheptane - Fenoxazoline - Tymazoline - Epinephrine
Topical: antiallergic agents, excluding corticosteroidsCromoglicic acid - Levocabastine - Azelastine - Antazoline - Spaglumic acid - Thonzylamine - Nedocromil - Olopatadine
Topical: corticosteroidsBeclometasone - Prednisolone - Dexamethasone - Flunisolide - Budesonide - Betamethasone - Tixocortol - Fluticasone - Mometasone furoate - Triamcinolone
Topical: other nasal preparationsCalcium hexamine thiocyanate - Retinol - Ipratropium bromide - Ritiometan - Mupirocin - Hexamidine - Framycetin
Systemic use: SympathomimeticsPhenylpropanolamine - Pseudoephedrine - Phenylephrine
v • d • e
Stimulants
EugeroicsAdrafinil • Armodafinil • Carphedon • Modafinil
Phenethylamines

4-Fluoroamphetamine • 4-Fluoromethamphetamine • 4-Methylmethcathinone • 4-MTA • α-PPP • Amphechloral • Amphetamine (Dexamphetamine, Adderall) • Amphetaminil • Benzphetamine • Bupropion • Cathinone • Chlorphentermine • Clobenzorex • Clortermine • Cypenamine • Diethylpropion • Dimethoxyamphetamine • Dimethylamphetamine • Dimethylcathinone • Diphenyl prolinol • Ephedrine • Epinephrine • Ethcathinone • Ethylamphetamine • Fencamfamine • Fenethylline • Fenfluramine • Fenproporex • Feprosidnine • Furfenorex • Levomethamphetamine • Lisdexamfetamine • MDMA • Mefenorex • Methamphetamine • Methcathinone • Methoxyphedrine • Methylone • Octopamine • Parahydroxyamphetamine • PMA • PMEA • PMMA • PPAP • Phendimetrazine • Phenmetrazine • Phentermine • Phenylephrine • Phenylpropanolamine • Prolintane  Propylamphetamine • Pseudoephedrine • Selegiline • Synephrine • Xylopropamine

Piperazines

BZP • MeOPP • MBZP • mCPP • 2C-B-BZP

XanthinesCaffeine • Aminophylline • Paraxanthine • Theobromine • Theophylline
Tropanes

Brasofensine • CFT • Cocaethylene • Cocaine • Lometopane • RTI-121 • Tesofensine • Troparil

CholinergicsArecoline • Cotinine • Nicotine
ConvulsantsBicuculline • Gabazine • Pentetrazol • Picrotoxin • Strychnine • Thujone
Phenylaminooxazoles
Others
See also Sympathomimetic amines
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tuaminoheptane". A list of authors is available in Wikipedia.
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