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Alimemazine



Alimemazine
Systematic (IUPAC) name
N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine
Identifiers
CAS number 84-96-8
ATC code D04AA10 R06AD02, R06AD05
PubChem 5574
DrugBank APRD00258
Chemical data
Formula C18H22N2S 
Mol. mass 298.447 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C(AU)

Legal status
Routes Oral

Alimemazine (INN), also known as trimeprazine (former BAN and USAN; trade names Nedeltran, Panectyl, Repeltin, Therafene, Theralen, Theralene, Vallergan, Vanectyl, or Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine).[1] It also acts as a sedative and anti-emetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine (Thorazine), it is not used as an anti-psychotic treatment.[2] It is no longer available in the United States.[3]

References

  1. ^ PubChem CID 78032.
  2. ^ Drugbank:Trimeprazine.
  3. ^ MedlinePlus:Trimeprazine.
v • d • e
Antihistamines (primarily R06)
Aminoalkyl ethersBromazine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylaminesBrompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediaminesChloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivativesAlimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivativesBuclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic useAntazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical useBamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroidsAntazoline • Azelastine
Other antiallergicsEmedastine • Epinastine • Ketotifen • Olopatadine
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Alimemazine". A list of authors is available in Wikipedia.
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