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Triflubazam


Triflubazam
Systematic (IUPAC) name
5-methyl-1-phenyl-8-(trifluoromethyl)-1,5-benzodiazepine-2,4-dione
Identifiers
CAS number	22365-40-8
ATC code	?
PubChem	31157
Chemical data
Formula	C₁₇H₁₃F₃N₂O₂
Mol. mass	334.29
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Triflubazam is a drug which is a 1,5-benzodiazepine derivative, related to clobazam. It has sedative and anxiolytic effects, with a long half-life and duration of action.^[1]^[2]^[3]

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References

^ Itil TM, Akpinar S, Fink M: Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome. Current Therapeutic Research 1976; 19: 307-315
^ Csanalosi I, Pereira-Oran J, Case G, et al: Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis. Current Therapeutic Research 1977; 22: 166-171
^ Nicholson AN, Stone BM, Clarke CH. Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man. British Journal of Clinical Pharmacology. 1977 Oct;4(5):567-72.

[1]

v • d • e Benzodiazepines (N05BA, N05CD)
1,4-Benzodiazepines	Bromazepam • Camazepam • Chlordiazepoxide • Cinolazepam • Clonazepam • Clorazepate • Cyprazepam • Delorazepam • Diazepam • Doxefazepam • Elfazepam • Ethyl loflazepate • Fletazepam • Fludiazepam • Fosazepam • Flunitrazepam • Flurazepam • Flutoprazepam • Gidazepam • Halazepam • Iclazepam • Lorazepam • Lormetazepam • Meclonazepam • Medazepam • Menitrazepam • Metaclazepam • Nimetazepam • Nitrazepam • Nordazepam • Oxazepam • Phenazepam • Pinazepam • Pivoxazepam • Prazepam • Quazepam • QH-II-66 • Reclazepam • Sulazepam • Temazepam • Tetrazepam • Uldazepam
Triazolobenzodiazepines	Adinazolam • Alprazolam • Estazolam • Triazolam • Zapizolam
Imidazobenzodiazepines	Bretazenil • Flumazenil • Imidazenil • Loprazolam • Midazolam • Ro15-4513
Oxazolobenzodiazepines	Cloxazolam • Flutazolam • Haloxazolam • Mexazolam • Oxazolam
Thienobenzodiazepines	Brotizolam • Clotiazepam • Etizolam
1,5-Benzodiazepines	Arfendazam • Clobazam • Lofendazam • Triflubazam
2,3-Benzodiazepines	Girisopam • GYKI-52895 • Nerisopam • Tofisopam
Benzodiazepine Prodrugs	Avizafone • Rilmazafone
Others	Bentazepam • Ketazolam • Tifluadom • Zolazepam