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Tolazamide


Tolazamide
Systematic (IUPAC) name
3-azepan-1-yl-1-(4-methylphenyl)sulfonyl-urea
Identifiers
CAS number	1156-19-0
ATC code	A10BB05
PubChem	5503
DrugBank	APRD01267
Chemical data
Formula	C₁₄H₂₁N₃O₃S
Mol. mass	311.401 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	7 hours
Excretion	Renal (85%) and fecal (7%)
Therapeutic considerations
Licence data	US
Pregnancy cat.	C(AU) C(US)
Legal status	℞-only(US)
Routes	Oral

Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes. It is part of the sulfonamide family (ATC A10BB).

v • d • e Oral antidiabetic drugs and Insulin analogs (A10)
Biguanides	Metformin
Sulfonylureas	Chlorpropamide, Glibenclamide (Glyburide), Gliclazide, Glimepiride, Glipizide, Gliquidone, Tolazamide, Tolbutamide
Alpha-glucosidase inhibitors	Acarbose, Miglitol, Voglibose
Thiazolidinediones (TZD)	Pioglitazone, Rosiglitazone, Troglitazone
Meglitinides	Nateglinide, Repaglinide, Mitiglinide
Dipeptidyl peptidase-4 (DPP-4) inhibitors	Saxagliptin, Sitagliptin, Vildagliptin
Glucagon-like peptide-1 analog	Exenatide
Insulin analogs	fast acting (Insulin lispro, Insulin aspart, Insulin glulisine), intermediate-acting (NPH insulin), long acting (Insulin glargine, Insulin detemir)