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Tioconazole


Tioconazole
Systematic (IUPAC) name
1-[2-[(2-chlorothiophen-3-yl) methoxy]- 2-(2,4-dichlorophenyl)- ethyl]imidazole
Identifiers
CAS number	65899-73-2
ATC code	D01AC07 G01AF08
PubChem	5482
DrugBank	APRD01262
Chemical data
Formula	C₁₆H₁₃Cl₃N₂O S
Mol. mass	387.711 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Topical

Tioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names. Tioconazole ointments serve to treat women's vaginal yeast infections. They are available in one day doses, as opposed to the 7-day treatments more common in use in the past. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".

Additional recommended knowledge

Essential Laboratory Skills Guide

Weighing the right way

Daily Sensitivity Test

Side effects

Side effects (for the women's formulas) may include temporary burning/irritation of the vaginal area, moderate drowsiness, and headache similar to a sinus headache. Personal Product's 1-Day brand literature also includes upper respiratory infection in its list of side effects. These side effects may be only temporary, and do not interefere with the patient's comfort enough to outweight the end result.

References

Tioconazole

v • d • e Antifungals (D01 and J02)
Antibiotics	Griseofulvin • polyene antimycotics (Natamycin, Nystatin)
Topical azoles	imidazoles (Bifonazole, Clomidazole, Clotrimazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole) • triazoles (Fluconazole) • benzimidazole (Thiabendazole)
Other topicals	Ciclopirox • Ethylparaben • Flucytosine • Salicylic acid • Selenium sulfide • Tolnaftate • Undecylenic acid • allylamines (Amorolfine, Butenafine, Naftifine, Terbinafine)
For systemic use	Griseofulvin • allylamine (Terbinafine) • polyene antimycotic (Amphotericin B) • triazoles (Itraconazole, Posaconazole, Voriconazole) • echinocandins (Anidulafungin, Caspofungin, Micafungin)
Other	Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle

v • d • e Gynecological anti-infectives and antiseptics (G01)
Antibiotics	polyene antimycotic (Nystatin, Natamycin, Amphotericin B) - Candicidin - Chloramphenicol - Hachimycin - Oxytetracycline - Carfecillin - Mepartricin - Clindamycin - Pentamycin
Arsenic compounds	Acetarsol
Quinoline derivatives	Diiodohydroxyquinoline - Clioquinol - Chlorquinaldol - Dequalinium - Broxyquinoline - Oxyquinoline
Organic acids	Lactic acid - Acetic acid - Ascorbic acid
Sulfonamides	Sulfatolamide
Imidazole derivatives	Metronidazole - Clotrimazole - Miconazole - Econazole - Ornidazole - Isoconazole - Tioconazole - Ketoconazole - Fenticonazole - Azanidazole - Propenidazole - Butoconazole - Omoconazole - Oxiconazole - Flutrimazole
Triazole derivatives	Terconazole
Other	Clodantoin - Inosine - Policresulen - Nifuratel - Furazolidone - Methylrosaniline - Povidone-iodine - Ciclopirox - Protiofate - Lactobacillus fermentum - Copper usnate

Category: Imidazoles

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tioconazole". A list of authors is available in Wikipedia.