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Tiazofurin



Tiazofurin
IUPAC name 2-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
Identifiers
CAS number 60084-10-8
PubChem 457954
MeSH Tiazofurin
SMILES C1=C(N=C(S1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N
Properties
Molecular formula C9H12N2O5S
Molar mass 260.268
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Tiazofurin is an inhibitor of IMP dehydrogenase. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.[1]

References

  1. ^ Popsavin M, Torović L, Svircev M et al (2006). "Synthesis and antiproliferative activity of two new tiazofurin analogues with 2'-amido functionalities". Bioorg. Med. Chem. Lett. 16 (10): 2773-6. doi:10.1016/j.bmcl.2006.02.001. PMID 16495053.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tiazofurin". A list of authors is available in Wikipedia.
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