My watch list
my.chemeurope.com  
Login  

Thorpe reaction



The Thorpe reaction is a chemical reaction described as a self-condensation of aliphatic nitriles catalyzed by base to form enamines.[1][2][3]


Thorpe-Ziegler reaction

The Thorpe-Ziegler reaction or Ziegler method is the intramolecular modification with a dinitrile as a reactant and a cyclic ketone as the final reaction product after acidic hydrolysis. The reaction is conceptually related to the Dieckmann condensation.


References

  1. ^  Baron, H.; Remfry, F. G. P.; Thorpe, Y. F. J. Chem. Soc. 1904, 85, 1726.
  2. ^  Ziegler, K. et al. Ann. 1933, 504, 94.
  3. ^  Schaefer, J. P.; Bloomfield, J. J. Org. React. 1967, 15, 1. (Review)
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Thorpe_reaction". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE