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Tesofensine


Tesofensine
Systematic (IUPAC) name
(2R,3S)-3-(3,4-dichlorophenyl)-2-ethoxymethyl- 8-methyl-8-azabicyclo[3.2.1]octane
Identifiers
CAS number	402856-42-2
ATC code	?
PubChem	?
Chemical data
Formula	C₁₇H₂₃Cl₂N O
Mol. mass	328.28 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	Legal
Routes	?

Tesofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor, which also seems to increase the action of acetylcholine in the brain, probably due to downstream effects. It was originally researched for the treatment of Alzheimer's disease and Parkinson's Disease, but was subsequently dropped from development for these applications, and is now being researched for the treatment of obesity, presumably as an appetite suppressant. As of 2006 it was in Phase II trials for the treatment of obesity.[1]

Additional recommended knowledge

References

v • d • e Stimulants
Eugeroics	Adrafinil • Armodafinil • Carphedon • Modafinil
Phenethylamines	4-Fluoroamphetamine • 4-Fluoromethamphetamine • 4-Methylmethcathinone • 4-MTA • α-PPP • Amphechloral • Amphetamine (Dexamphetamine, Adderall) • Amphetaminil • Benzphetamine • Bupropion • Cathinone • Chlorphentermine • Clobenzorex • Clortermine • Cypenamine • Diethylpropion • Dimethoxyamphetamine • Dimethylamphetamine • Dimethylcathinone • Diphenyl prolinol • Ephedrine • Epinephrine • Ethcathinone • Ethylamphetamine • Fencamfamine • Fenethylline • Fenfluramine • Fenproporex • Feprosidnine • Furfenorex • Levomethamphetamine • Lisdexamfetamine • MDMA • Mefenorex • Methamphetamine • Methcathinone • Methoxyphedrine • Methylone • Octopamine • Parahydroxyamphetamine • PMA • PMEA • PMMA • PPAP • Phendimetrazine • Phenmetrazine • Phentermine • Phenylephrine • Phenylpropanolamine • Prolintane Propylamphetamine • Pseudoephedrine • Selegiline • Synephrine • Xylopropamine
Piperazines	BZP • MeOPP • MBZP • mCPP • 2C-B-BZP
Xanthines	Caffeine • Aminophylline • Paraxanthine • Theobromine • Theophylline
Tropanes	Brasofensine • CFT • Cocaethylene • Cocaine • Lometopane • RTI-121 • Tesofensine • Troparil
Cholinergics	Arecoline • Cotinine • Nicotine
Convulsants	Bicuculline • Gabazine • Pentetrazol • Picrotoxin • Strychnine • Thujone
Phenylaminooxazoles	4-Methyl-aminorex • Aminorex • Clominorex • Fenozolone • Fluminorex • Pemoline • Thozalinone
Others	Amineptine • Bemegride • BPAP • Clenbuterol • Clofenciclan • Cyclopentamine • Cyprodenate • Desoxypipradrol • Ethylphenidate • Ethamivan • Gilutensin • GYKI-52895 • Hexacyclonate • Indanorex • Indatraline • Isometheptene • Mazindol • MDPV • Mesocarb • Methylphenidate (Dexmethylphenidate) • Naphthylisopropylamine • Nikethamide • Nocaine • Nomifensine • Phacetoperane • Phthalimidopropiophenone • Pipradrol • Prolintane • Propylhexedrine • Pyrovalerone • Sibutramine • Tuamine • Vanoxerine • Yohimbine • Zylofuramine
See also Sympathomimetic amines

Categories: Serotonin-norepinephrine-dopamine reuptake inhibitors | Tropanes | Stimulants | Sympathomimetic amines

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tesofensine". A list of authors is available in Wikipedia.

Tesofensine

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References

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