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Table of medication secernated in kidney



This is a table of medication secernated (secreted) in kidney.

Acid medication are, because of pH parturition, secreted to a higher extent when urine is basic. In the same way, basic medications are secreted to a higher extent when urine is acidic.

Medication Location Acid or base [1] anion or cation[2] Percentage excreted[3]
para-aminohippurate proximal tubule[4] Acid anion
furosemide proximal tubule[4] Acid anion 100-75
glucuronic acid-conjugates proximal tubule[4] Acid
glycine conjugates proximal tubule[4] Acid
indometacin proximal tubule[4] Acid anion
methotrexate proximal tubule[4] Acid 100-75
penicillin proximal tubule[4] Acid anion 75-50
(benzylpenicillin)
probenecid proximal tubule[4] Acid anion
sulphate conjugates proximal tubule[4] Acid
thiazide diuretics proximal tubule[4] Acid
uric acid proximal tubule[4] Acid
amiloride proximal tubule[4] Base cation
dopamine proximal tubule[4] Base
histamine proximal tubule[4] Base
mepacrine proximal tubule[4] Base
morphine proximal tubule[4] Base cation
pethidine proximal tubule[4] Base
quaternary ammonium compounds proximal tubule[4] Base
quinine proximal tubule[4] Base cation
5 hydroxytryptamine proximal tubule[4] Base
triamterene proximal tubule[4] Base
gentamicin 100-75
atenolol 100-75
digoxin 100-75
cimetidine cation 75-50
tetracycline 75-50
(oxytetracycline)
neostigmine 75-50
propantheline ~50
tubocurarine ~50
acetazolamide proximal tubule[5] anion
chlorothiazide proximal tubule[5] anion
saccharin proximal tubule[5] anion
salicylate proximal tubule[5] anion
atropine proximal tubule[5] cation
NMN proximal tubule[5] cation
paraquat proximal tubule[5] cation
procainamide proximal tubule[5] cation
tetraethylammonium proximal tubule[5] cation
chlorpromazine proximal tubule[5] cation

References

  1. ^ Unless else specified in table boxes, then ref is Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 112
  2. ^ Unless else specified in table boxes, then ref is Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3.  Page 802
  3. ^ Unless else specified in table boxes, then ref is Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 113
  4. ^ a b c d e f g h i j k l m n o p q r s t u Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 112
  5. ^ a b c d e f g h i j Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3.  Page 802
v • d • e
Urinary system, physiology: renal physiology and acid base physiology
FiltrationRenal blood flow - Ultrafiltration - Countercurrent exchange
Hormones affecting filtrationAntidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide
Secretion/clearancePharmacokinetics - Clearance of medications
ReabsorptionSolvent drag -Na+ - Cl- -urea -glucose -oligopeptides -protein
EndocrineRenin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins
Assessing Renal function / Measures of dialysisGlomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance (Effective renal plasma flow - Extraction ratio)
Acid base physiologyFluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas
Buffering/compensationBicarbonate buffering system - Respiratory compensation - Renal compensation
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Table_of_medication_secernated_in_kidney". A list of authors is available in Wikipedia.
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