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T-type calcium channel

calcium channel, voltage-dependent, T type, alpha 1G subunit
Identifiers
Symbol	CACNA1G
Entrez	8913
HUGO	1394
OMIM	604065
RefSeq	NM_018896
UniProt	O43497
Other data
Locus	Chr. 17 q22

calcium channel, voltage-dependent, T type, alpha 1H subunit
Identifiers
Symbol	CACNA1H
Entrez	8912
HUGO	1395
OMIM	607904
RefSeq	NM_001005407
UniProt	O95180
Other data
Locus	Chr. 16 p13.3

calcium channel, voltage-dependent, T type, alpha 1I subunit
Identifiers
Symbol	CACNA1I
Entrez	8911
HUGO	1396
OMIM	608230
RefSeq	NM_001003406
UniProt	Q9P0X4
Other data
Locus	Chr. 22 q13.1

The T-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties.

Additional recommended knowledge

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T-type calcium channel blockers are used primarily as antiepileptics.

v • d • e Membrane transport protein: ion channels
Ca²⁺: Calcium channel	Voltage-dependent calcium channel (L-type/Ca_vα(1.1, 1.2, 1.3, 1.4), N-type, P-type/Ca_vα(2.1), Q-type, R-type, T-type, β-subunits (β1, β2, β4), γ-subunits (γ2) • Inositol triphosphate receptor • Ryanodine receptor • Cation channels of sperm • Two-pore channel
Na⁺: Sodium channel	Na_vα (1.1, 1.2, 1.4, 1.5, 1.7, 1.9) • Na_vβ (1, 3, 4) • Epithelial sodium channel
K⁺: Potassium channel	Voltage-gated (K_vα (1.1, 1.2, 1.3, 1.4, 1.5, 2.1, 4.2, 4.3, 7.1, 7.2, 7.3, 7.4, 10.1, 11.1/hERG) • K_vβ (1, 2), Shaker gene, KCNE1) • Calcium-activated (BK channel, SK channel, SK3) • Inward-rectifier K_ir (1.1, 2.1, 2.2, 2.3, 3.1, 3.2, 3.4, 4.1, 4.2, 6.1, 6.2)) • Tandem pore domain K2P (1, 2, 3, 4, 6, 9)
Cl^-: Chloride channel	Cystic fibrosis transmembrane conductance regulator
Porin	Aquaporin (1, 2, 3, 4) • Voltage-dependent anion channel (1)
Cations: TRP	TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (Mucolipin-1) • TRPP (1, 2)• TRPV (1, 2, 3, 4, 5, 6)
Other/general	Voltage-gated ion channel • Ligand-gated ion channel • Cyclic nucleotide-gated ion channel (α1, α3, β3, H1, H2, H4) • Stretch-activated ion channel