Sulbutiamine

Sulbutiamine (brand name: Arcalion®) is a precursor to thiamine (i.e., vitamin B₁). It is indicated for the treatment of asthenia.^[1] Furthermore, the ability of sulbutiamine to reduce fatigue is considered desirable by athletes, and it is available for over-the-counter sale as a nutritional supplement. Additionally, the demonstrated ability of sulbutiamine to improve memory in rats^[2] and patients of schizophrenia^[2] suggests that it is a nootropic.

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Effects

Sulbutiamine reduces fatigue, memory difficulties, intellectual tiredness and may speed convalescence.^[3]

Dosage

Sulbutiamine is sometimes supplied in 200 mg tablets. The proper therapeutic dosage has been reported to be 12.5 mg/kg,^[2] which corresponds to 850 mg for a 68 kg (150 lb) person. However, it should be noted that dosage recommendations vary; the manufacturer of Arcalion, for example, recommends no more than 600 mg per day.

References