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Stephen aldehyde synthesisStephen aldehyde synthesis, a named reaction in chemistry, was invented by Henry Stephen (OBE/MBE). This reaction involves the preparation of aldehydes (R-CHO) from nitriles (R-CN) using tin(II) chloride (SnCl2), hydrochloric acid (HCl) and quenching the resulting iminium salt ([R-CH=NH2]+Cl-) with water (H2O).[1] Additional recommended knowledgeOverall, the reaction scheme is as follows: References
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Stephen_aldehyde_synthesis". A list of authors is available in Wikipedia. |