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Sanguinarine
Sanguinarine is a toxic alkaloid extracted from some plants, including Bloodroot (Sanguinaria canadensis), Mexican Prickly Poppy Argemone mexicana,[1] Chelidonium majus and Macleaya cordata. Additional recommended knowledgeSanguinarine kills animal cells through its action on the Na+-K+-ATPase transmembrane protein. Epidemic dropsy is a disease that results from ingesting sanguinarine. If applied to the skin, sanguinarine kills cells and may destroy tissue. In turn, the bleeding wound may produce a massive scab, called an Eschar. For this reason, sanguinarine is termed an escharotic. In plants, sanguinarine is synthesized from dihydrosanguinarine through the action of Dihydrobenzophenanthridine oxidase (EC 1.5.3.12). References
Categories: Alkaloids | Quaternary ammonium compounds |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Sanguinarine". A list of authors is available in Wikipedia. |