Ruthenium red

Ruthenium red is a Ruthenium containing red staining dye.

Additional recommended knowledge

What is the Sensitivity of my Balance?

Essential Laboratory Skills Guide

Don't let static charges disrupt your weighing accuracy

The organic Ruthenium Red is polycationic cell biology reagent that tightly binds to tubulin dimers and Ryanodine receptor. It is a potent inhibitor of intracellular calcium release by Ryanodine receptors at nanomolar concentrations (km ~20 nM). ^[1]

The inorganic dye ammoniated ruthenium oxychloride used in histology to stain aldehyde fixed mucopolysaccharides, is sometimes also called Ruthenium red, and inhibits calcium transport through membrane channels.

References

1. ^ TRIPATHY, LE XU ASHUTOSH, PASEK, DANIEL A., MEISSNER, GERHARD Potential for Pharmacology of Ryanadine Receptor/Calcium Release Channels Ann NY Acad Sci 1998 853: 130-148 [1]