Roflumilast

Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor which, due to its selective inhibition of the PDE4 isoenzyme, has potential antiinflammatory and antimodulatory effects in the pulmonary system.

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Daily Sensitivity Test

Karish SB, Gagnon JM. Ann Pharmacother. 2006 May 30

Roflumilast(3-cyclopropylmethoxy-4 difluromethoxy-n-[3,5-dicloropyrid-4yl]-benzamide) is a selective pde4 inhibitor developed by altana pharma.Inhibition of pde4 theoretically leads to inhibition of proinflammatory mediators and the clinical effects of inhibition of bronchoconstriction,chemotaxis,and inflammation

Prashant R. Shirode Mumbai( INDIA )