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Quinuclidine
Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block. It is a strong base with pKa of the conjugate acid of 19.5 ranking it between triethylamine (18.5) and DBN (23.8). This is due to greater availability of the nitrogen lone pair[citation needed]. It can be prepared by reduction of quinuclidone. Additional recommended knowledgeThe compound is structurally related to DABCO in which the other bridgehead is also nitrogen and tropane with a slightly different carbon frame. A biomolecule with the quinuclidine framework is quinine. |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Quinuclidine". A list of authors is available in Wikipedia. |