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Quazepam



Quazepam
Systematic (IUPAC) name
7-chloro-5-(o-fluorophenyl)-1,3-
dihydro-1-(2,2,2-trifluoroethyl)-
2H-1,4-benzodiazepin-2-thione
Identifiers
CAS number 36735-22-5
ATC code N05CD10
PubChem 4999
DrugBank ?
Chemical data
Formula C17H11ClF4N2S 
Mol. mass 386.795 g/mol
Pharmacokinetic data
Bioavailability 29–35%
Metabolism Hepatic
Half life 39 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.

X(AU) X(US)

Legal status

Schedule IV(US)

Routes Oral

Quazepam (marketed under brand names Doral, Dormalin) is a drug which is a benzodiazepine derivative. Quazepam induces impairment of motor function and has hypnotic properties.[1]

Quazepam is used to treat insomnia. Usual dosage is 7.5 to 15 mg orally at bedtime. Side effects include drowsiness, loss of coordination, unsteady gait, dizziness, lightheadedness, and slurred speech. It is long-acting benzodiazepine.

References

  1. ^ Yasui M; Kato A, Kanemasa T, Murata S, Nishitomi K, Koike K, Tai N, Shinohara S, Tokomura M, Horiuchi M, Abe K. (Jun 2005). "[Pharmacological profiles of benzodiazepinergic hypnotics and correlations with receptor subtypes]" 25 (3): 143-51. PMID 16045197.
v • d • e
Benzodiazepines (N05BA, N05CD)
1,4-Benzodiazepines
Triazolobenzodiazepines
Imidazobenzodiazepines
Oxazolobenzodiazepines
ThienobenzodiazepinesBrotizolam • Clotiazepam • Etizolam
1,5-BenzodiazepinesArfendazam • Clobazam • Lofendazam • Triflubazam
2,3-BenzodiazepinesGirisopam • GYKI-52895 • Nerisopam • Tofisopam
Benzodiazepine ProdrugsAvizafone • Rilmazafone
OthersBentazepam • Ketazolam • Tifluadom • Zolazepam
v • d • e
Psycholeptics: hypnotics and sedatives (N05C)
BarbituratesPentobarbital - Amobarbital - Butobarbital - Barbital - Aprobarbital - Secobarbital - Talbutal - Vinylbital - Vinbarbital - Cyclobarbital - Heptabarbital - Reposal - Methohexital - Hexobarbital - Thiopental - Ethallobarbital - Allobarbital - Proxibarbal - Phenobarbital
AldehydesAcetylglycinamide chloral hydrate - Chloral hydrate - Chloralodol - Dichloralphenazone - Paraldehyde - Petrichloral
BenzodiazepineBrotizolam - Cinolazepam - Doxefazepam - Estazolam - Flunitrazepam - Flurazepam - Loprazolam - Lorazepam - Lormetazepam - Nitrazepam - Nimetazepam - Midazolam - Quazepam - Temazepam - Triazolam
PiperidinedioneGlutethimide - Methyprylon - Pyrithyldione
QuinazolinoneAfloqualone - Cloroqualone - Diproqualone - Etaqualone - Mebroqualone - Mecloqualone - Methaqualone - Methylmethaqualone
NonbenzodiazepineCL-218,872 - Eszopiclone - Indiplon - Necopidem - Pazinaclone - Saripidem - Suproclone - Suriclone - SX-3228 - Zaleplon - Zolpidem - Zopiclone
Melatonin receptorAgomelatine - Melatonin - Ramelteon
GHB TypeGABOB - GHB - GBL - 1,4-Butanediol
OtherApronal - Bromides - Bromisoval - Carbromal - Clomethiazole - Dexmedetomidine - Embutramide - Ethchlorvynol - Ethinamate - Hexapropymate - Methylpentynol - Niaprazine - Propiomazine - Scopolamine - Sulfonmethane - Trichloroethanol - Triclofos - Valerian - Valnoctamide
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Quazepam". A list of authors is available in Wikipedia.
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