Pyrovalerone

Pyrovalerone (Centroton, Thymergix) is a stimulant drug developed in the late 1960s and used in France and some other European countries. It is sometimes prescribed for treating chronic fatigue and lethargy^[1] or as an appetite suppresant, though it is used infrequently due to problems with abuse and dependence. ^[2] Side effects of pyrovalerone include loss of appetite, anxiety, insomnia, and tremor. Withdrawal syndrome following abuse causes depression. ^[3] Pyrovalerone is a Schedule 5 drug in the USA. It is closely related to some other stimulant drugs such as prolintane and MDPV.

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CAS# 1147-62-2 (pyrovalerone hydrochloride); 3563-49-3 (pyrovalerone freebase)

References

1. ^ Gardos G, Cole JO. Evaluation of pyrovalerone in chronically fatigued volunteers. Current Therapeutic Research, Clinical and Experimental. 1971 Oct;13(10):631-5.
2. ^ Deniker P, Loo H, Cuche H, Roux JM. Abuse of pyrovalerone by drug addicts. Annales Medico-Psychologiques (Paris) 1975 Nov;2(4):745-8.
3. ^ http://www.biam2.org/www/Etr8623.html