To use all functions of this page, please activate cookies in your browser.
my.chemeurope.com
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
PolymyxinPolymyxins are cationic detergent antibiotics, with a general structure of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins have a bactericidal effect on Gram-negative bacilli, especially on Pseudomonas and coliform organisms. Polymyxin antibiotics are highly neurotoxic and nephrotoxic[citations needed], and very poorly absorbed from the gastrointestinal tract. Polymyxins also have antifungal activity. Additional recommended knowledgeWell known examples: Polymyxin acts as an antibiotic by damaging the cytoplasmic membrane of bacteria. Also polymyxins biological source is Bacillius polymyxa. See also
Categories: Polymyxin antibiotics | Antimicrobial peptides |
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Polymyxin". A list of authors is available in Wikipedia. |