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Pivampicillin


Pivampicillin
Systematic (IUPAC) name
2,2-dimethylpropanoyloxymethyl (2S,5R,6R)- 6-{[(2R)-2-amino-2-phenyl-acetyl]amino}-3,3- dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0] heptane-2-carboxylate
Identifiers
CAS number	33817-20-8
ATC code	J01CA02
PubChem	33478
Chemical data
Formula	C₂₂H₂₉N₃O₆S
Mol. mass	463.548 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	Renal (76%)
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Oral

Pivampicillin is a pivaloyloxymethylester of ampicillin. It is a prodrug, which is thought to enhance the oral bioavailability of ampicillin because of its greater lipophilicity compared to that of ampicillin.

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v • d • e Antibacterials for systemic use: beta-lactam antibiotics - penicillins (J01C)
Antibiotics	Amoxicillin • Ampicillin • Azlocillin • Carbenicillin • Cloxacillin • Dicloxacillin • Flucloxacillin • Mezlocillin • Nafcillin • Piperacillin • Pivampicillin • Ticarcillin
Beta-lactamase inhibitors	Sulbactam • Tazobactam • Clavulanic acid
Combinations	Ampicillin/sulbactam (Sultamicillin) • Co-amoxiclav