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Pinolenic acid
Pinolenic acid (often misspelled as Pinoleic acid) is a fatty acid contained in the Korean Pine nut and the seeds of other conifers (Taxaceae). The highest percentage of pinolenic acid is found in Siberian pine nuts and the oil produced by them. Additional recommended knowledgeChemistry and biochemistryPinolenic acid is formally designated as all-cis-5,9,12-18:3.[1] [2] Some sources also use the term columbinic acid for this substance.[2] But columbinic acid sometimes designates an E-Z isomer (trans,cis,cis delta-5,9,12/18:3) in the biologic literature.[3] Pinolenic acid is an isomer of gamma-linolenic acid (GLA). GLA is an ω-6 essential fatty acid (EFA) but pinolenic acid is not. However, like the EFAs, it forms biologically active metabolites in the presence of cyclooxygenase or lipoxygenase. These metabolites can partially relieve some of the symptoms of EFA deficiency.[4] PhysiologyRecent research has shown its potential use in weight loss by curbing the appetite.[5] Pinolenic acid causes the triggering of two hunger suppresants—cholecystokinin and glucagon-like peptides. Pinolenic acid may have LDL-lowering properties by enhancing hepatic LDL uptake.[6] It is sometimes used as a pesticide.[7] References
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Pinolenic_acid". A list of authors is available in Wikipedia. |