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Phosphocholine



Phosphocholine
Identifiers
CAS number 107-73-3
PubChem 1014
MeSH Phosphocholine
SMILES C[N+](C)(C)CCOP(O)(O)=O
Properties
Molecular formula C5H15NO4P+
Molar mass 184.151
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Phosphocholine (PC) is an intermediate in the synthesis of phosphatidylcholine in tissues. It is a molecule found for example in lecithin.

It is also used by nematodes and human placentas to suppress an immune response by their hosts. [1] It is one of the natural constituents of hens' eggs (and many other eggs), in the form of Egg-PC, which is often used in biomimetic membrane studies.[2] It can be purchased in purified form from many sources. The PC group is usually divided into natural (like EggPC) and synthetic products.

Natural phospholipid derivates: egg PC, egg PG, soy PC, hydrogenated soy PC, sphingomyelin as natural phospholipids.

Synthetic phospholipid derivates: phosphocholine (DDPC, DLPC, DMPC, DPPC, DSPC, DOPC, POPC, DEPC), phosphoglycerol (DMPG, DPPG, DSPG, POPG), phosphatidic acid (DMPA, DPPA, DSPA), phosphoethanolamine (DMPE, DPPE, DSPE DOPE), phoshoserine (DOPS), PEG phospholipid (mPEG-phospholipid, polyglycerin-phospholipid, funcitionilized-phospholipid, terminal activated-phosholipid)

Abbreviations used and Chemical Information

Abbreviation CAS Name
DDPC 3436-44-0 1,2-Didecanoyl-sn-Glycero-3-phosphocholine
DEPA-NA 80724-31-8 1,2-Dierucoyl-sn-Glycero-3-Phosphate(Sodium Salt)
DEPC 56649-39-9 1,2-Erucoyl-sn-Glycero-3-phosphocholine
DEPE 988-07-2 1,2-Dierucoyl-sn-Glycero-3-phosphoethanolamine
DEPG-NA 1,2-Dierucoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DLOPC 998-06-1 1,2-Linoleoyl-sn-Glycero-3-phosphocholine
DLPA-NA 1,2-Dilauroyl-sn-Glycero-3-Phosphate(Sodium Salt)
DLPC 18194-25-7 1,2-Dilauroyl-sn-Glycero-3-phosphocholine
DLPE 1,2-Dilauroyl-sn-Glycero-3-phosphoethanolamine
DLPG-NA 1,2-Dilauroyl-sn-Glycero-3[Phospho-rac-(1-glycerol...) (Sodium Salt)
DLPG-NH4 1,2-Dilauroyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DLPS-NA 1,2-Dilauroyl-sn-Glycero-3-phosphoserine(Sodium Salt)
DMPA-NA 80724-3 1,2-Diimyristoyl-sn-Glycero-3-Phosphate(Sodium Salt)
DMPC 18194-24-6 1,2-Dimyristoyl-sn-Glycero-3-phosphocholine
DMPE 988-07-2 1,2-Dimyristoyl-sn-Glycero-3-phosphoethanolamine
DMPG-NA 67232-80-8 1,2-Myristoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DMPG-NH4 108321-03-5 1,2-Myristoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DMPG-NH4/NA 1,2-Myristoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DMPS-NA 1,2-Dimyristoyl-sn-Glycero-3-phosphoserine(Sodium Salt)
DOPA-NA 1,2-Dioleoyl-sn-Glycero-3-Phosphate(Sodium Salt)
DOPC 4235-95-4 1,2-Dioleoyl-sn-Glycero-3-phosphocholine
DOPE 4004-5-1- 1,2-Dioleoyl-sn-Glycero-3-phosphoethanolamine
DOPG-NA 62700-69-0 1,2-Dioleoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DOPS-NA 70614-14-1 1,2-Dioleoyl-sn-Glycero-3-phosphoserine(Sodium Salt)
DPPA-NA 71065-87-7 1,2-Dipalmitoyl-sn-Glycero-3-Phosphate(Sodium Salt)
DPPC 63-89-8 1,2-Dipalmitoyl-sn-Glycero-3-phosphocholine
DPPE 923-61-5 1,2-Dipalmitoyl-sn-Glycero-3-phosphoethanolamine
DPPG-NA 67232-81-9 1,2-Dipalmitoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DPPG-NH4 73548-70-6 1,2-Dipalmitoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DPPS-NA 1,2-Dipalmitoyl-sn-Glycero-3-phosphoserine(Sodium Salt)
DSPA-NA 108321-18-2 1,2-Distearoyl-sn-Glycero-3-Phosphate(Sodium Salt)
DSPC 816-94-4 1,2-Distearoyl-sn-Glycero-3-phosphocholine
DSPE 1069-79-0 1,2-Diostearpyl-sn-Glycero-3-phosphoethanolamine
DSPG-NA 67232-82-0 1,2-Distearoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DSPG-NH4 108347-80-4 1,2-Distearoyl-sn-Glycero-3[Phospho-rac-(1-glycerol...)
DSPS-NA 1,2-Distearoyl-sn-Glycero-3-phosphoserine(Sodium Salt)
Egg Sphingomyelin empty Liposome
EPC Egg-PC
HEPC Hydrogenated Egg PC
HSPC High purity Hydrogenated Soy PC
HSPC Hydrogenated Soy PC
LYSOPC MYRISTIC 18194-24-6 1-Myristoyl-sn-Glycero-3-phosphocholine
LYSOPC PALMITIC 17364-16-8 1-Palmitoyl-sn-Glycero-3-phosphocholine
LYSOPC STEARIC 19420-57-6 1-Stearoyl-sn-Glycero-3-phosphocholine
Milk Sphingomyelin MPPC 1-Myristoyl,2-palmitoyl-sn-Glycero 3-phosphocholine
MSPC 1-Myristoyl,2-stearoyl-sn-Glycero-3–phosphocholine
PMPC 1-Palmitoyl,2-myristoyl-sn-Glycero-3–phosphocholine
POPC 26853-31-6 1-Palmitoyl,2-oleoyl-sn-Glycero-3-phosphocholine
POPE 1-Palmitoyl-2-oleoyl-sn-Glycero-3-phosphoethanolamine
POPG-NA 81490-05-3 1,2-Dioleoyl-sn-Glycero-3[Phospho-rac-(1-glycerol)...](Sodium Salt)
PSPC 1-Palmitoyl,2-stearoyl-sn-Glycero-3–phosphocholine
SMPC 1-Stearoyl,2-myristoyl-sn-Glycero-3–phosphocholine
SOPC 1-Stearoyl,2-oleoyl-sn-Glycero-3-phosphocholine
SPPC 1-Stearoyl,2-palmitoyl-sn-Glycero-3-phosphocholine

References

  1. ^ http://news.bbc.co.uk/2/hi/health/7081298.stm
  2. ^ Rose L and Jenkins ATA (2006). "The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes". Bioelectrochem. 71 (1): 114-120. Entrez PubMed 16875886

See also
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phosphocholine". A list of authors is available in Wikipedia.
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