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PLAT domain
PLAT domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase Pfam PF01114, which mediates membrane association. Additional recommended knowledgeThis domain is found in a variety of membrane or lipid associated proteins. It forms a beta-sandwich composed of two sheets of four strands each[1][2][3]. Human proteins containing this domainALOX12; ALOX12B; ALOX12P2; ALOX15; ALOX15B; ALOX5; ALOXE3; LIPC; LIPG; LOXHD1; LPL; PKD1; PKD1L1; PKD1L2; PKD1L3; PKDREJ; PNLIP; PNLIPRP1; PNLIPRP2; PNLIPRP3; RAB6IP1; References
This article includes text from the public domain Pfam and InterPro IPR001024 Categories: Protein domains | Peripheral membrane proteins |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "PLAT_domain". A list of authors is available in Wikipedia. |