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Oxyphenisatine


Oxyphenisatine
Systematic (IUPAC) name
3,3-bis(4-hydroxyphenyl)-1H-indol-2-one
Identifiers
CAS number	?
ATC code	A06AB01
PubChem	31315
Chemical data
Formula	C₂₀H₁₅N O₃
Mol. mass	317.338 g/mol
Pharmacokinetic data
Bioavailability	poor
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	banned
Routes	oral,rectal

Oxyphenisatine (or oxyphenisatin acetate) is a laxative. It is closely related to Bisacodyl (Brand name: Dulcolax), Sodium Picosulfate, and Phenolthalein. It has been suggested that it is the laxative component in prunes. Long term use is associated with liver damage, and as a result, it was banned by the United States Food and Drug Administration in the early 1970's. Most of the rest of the world follows the FDA lead, so it is no longer available in most of the world.

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v • d • e Laxatives (A06)
Softeners, emollients	Paraffin - Docusate sodium
Contact laxatives	Oxyphenisatine - Bisacodyl - Dantron - Phenolphthalein - Castor oil - Senna glycosides - Cascara - Sodium picosulfate - Bisoxatin
Bulk producers	Ispaghula - Ethulose - Sterculia - Linseed - Methylcellulose - Triticum - Polycarbophil calcium
Osmotically acting laxatives	Magnesium carbonate - Magnesium oxide - Magnesium peroxide - Magnesium sulfate - Lactulose - Lactitol - Sodium sulfate - Pentaerithrityl - Macrogol - Mannitol - Sodium phosphate - Sorbitol - Magnesium citrate - Sodium tartrate
Enemas	Sodium phosphate - Bisacodyl - Dantron - Glycerol - Oil - Sorbitol