Nucleoside-specific porin


Nucleoside-specific channel-forming protein, Tsx
Identifiers
Symbol	Channel_Tsx
Pfam	PF03502
InterPro	IPR003055
TCDB	1.B.10
OPM family	71
OPM protein	1tly
Available PDB structures: 1tlyB:55-205 1tlwB:55-205 1tlzA:55-205

Nucleoside-specific porin (the tsx gene of Escherichia coli) is an outer membrane protein, Tsx, which constitutes the receptor for colicin K and Bacteriophage T6, and functions as a substrate-specific channel for nucleosides and deoxy-nucleosides^[1]. The protein contains 294 amino acids, the first 22 of which are characteristic of a bacterial signal sequence peptide. Tsx shows no significant similarities to general bacterial porins.

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References

^ Bremer E, Martinussen J, Middendorf A, Valentin-Hansen P (1990). "Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli". Gene 96 (1): 59-65. PMID 2265760.

This article includes text from the public domain Pfam and InterPro IPR003055

Categories: Protein domains | Protein families | Outer membrane proteins