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Nifuroxazide



Nifuroxazide
Systematic (IUPAC) name
4-Hydroxybenzoic acid [(5-nitro-2-furanyl)methylene]hydrazide
Identifiers
CAS number 965-52-6
ATC code A07AX03
PubChem 5337997
Chemical data
Formula C12H9N3O5 
Mol. mass 275.2 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral

Nifuroxazide (INN) is an oral nitrofuran antibiotic used to treat colitis and diarrhea. It is sold under the brand names Ambatrol, Antinal, Bacifurane, Nifrozid, Ercefuryl, and Endiex (CZ, SK, PL). It is sold in capsule form and also as a suspension.

Maurice Claude Ernest Carron patented the drug in the United States in 1966 [1]. Subsequent patents issued to Germano Cagliero of Marxer S.p.A describe the use of nifuroxazide as an antibiotic used to treat livestock.[2]

Notes

  1. ^ USPTO No. 3290213 |http://www.google.com/patents?id=f2dwAAAAEBAJ
  2. ^ USPTO No 4093746 |http://www.google.com/patents?vid=USPAT4093746
v • d • e
Antidiarrheals, intestinal anti-inflammatory/anti-infective agents (A07)
Intestinal anti-infectivesAntibiotics (Neomycin, Nystatin, Natamycin, Streptomycin, Polymyxin B, Paromomycin, Amphotericin B, Kanamycin, Vancomycin, Colistin, Rifaximin)

Sulfonamides (Phthalylsulfathiazole, Sulfaguanidine, Succinylsulfathiazole)

other (Miconazole, Broxyquinoline, Acetarsol, Nifuroxazide, Nifurzide)
Intestinal adsorbentsCharcoal - Bismuth - Pectin - Kaolin - Crospovidone - Attapulgite - Diosmectite
AntipropulsivesDiphenoxylate - Opium - Loperamide - Difenoxin
Intestinal anti-inflammatory agentscorticosteroids acting locally (Prednisolone, Hydrocortisone, Prednisone, Betamethasone, Tixocortol, Budesonide, Beclometasone)

antiallergic agents, excluding corticosteroids (Cromoglicic acid)

aminosalicylic acid and similar agents (Sulfasalazine, Mesalazine, Olsalazine, Balsalazide)
Antidiarrheal micro-organismsSaccharomyces boulardii
Other antidiarrhealsAlbumin tannate - Ceratonia - Racecadotril
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nifuroxazide". A list of authors is available in Wikipedia.
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