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N-Oxalylglycine



N-Oxalylglycine
IUPAC name N-oxalylglycine
Other names NOG
Identifiers
CAS number 5262-39-5
Properties
Molecular formula C4H5NO5
Molar mass 147.1
Appearance colourless solid
Solubility in water water, dmso
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

N-Oxalylglycine is the organic compound with the formula HO2CC(O)NHCH2CO2H. This colourless solid is used as an inhibitor of α-ketoglutarate-dependent enzymes.[1] It is isosteric with α-ketoglutaric acid. Such enzymes are pervasive and, for example, are required for the synthesis of 4-hydroxyproline.

References

  1. ^ Hausinger, R. P."Fe(II)/α-ketoglutarate-dependent hydroxylases and related enzymes" Critical Reviews of Biochemical Molecular Biology 2004, 39: pp 21-68.DOI: 10.1080/10409230490440541
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "N-Oxalylglycine". A list of authors is available in Wikipedia.
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