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Mevastatin


Mevastatin
Systematic (IUPAC) name
Compactin
Identifiers
CAS number	73573-88-3
ATC code	?
PubChem	64715
DrugBank	EXPT00012
Chemical data
Formula	C₂₃H₃₆O₆
Mol. mass	408.534 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Mevastatin, compactin, ML-236B is a hypolipidemic agent that belongs to the statins class.

Additional recommended knowledge

Safe Weighing Range Ensures Accurate Results

Essential Laboratory Skills Guide

Don't let static charges disrupt your weighing accuracy

It was the first compound isolated in the 70s during research into HMG-CoA reductase inhibitors produced by a mould Penicillium citrinum.

Mevastatin is not used in therapy of hyperlipidemias because of multiple side effects but it is the only source for production of other statin - pravastatin.

v • d • e Lipid modifying agents (C10)
Statins	Atorvastatin • Cerivastatin • Fluvastatin • Lovastatin • Mevastatin • Pitavastatin • Pravastatin • Rosuvastatin • Simvastatin
Fibrates	Clofibrate • Bezafibrate • Aluminium clofibrate • Gemfibrozil • Fenofibrate • Simfibrate • Ronifibrate • Ciprofibrate • Etofibrate • Clofibride
Bile acid sequestrants	Colestyramine • Colestipol • Colextran • Colesevelam
Niacin and derivatives	Niceritrol • Niacin • Nicofuranose • Aluminium nicotinate • Nicotinyl alcohol • Acipimox
Other	Dextrothyroxine • Probucol • Tiadenol • Benfluorex • Meglutol • Omega-3-triglycerides • Magnesium pyridoxal 5-phosphate glutamate • Policosanol • Ezetimibe