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Mebhydrolin



Mebhydrolin
Systematic (IUPAC) name
9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-β-carboline
Identifiers
CAS number 524-81-2
6153-33-9[1]
ATC code R06AX15
PubChem 10458737
Chemical data
Formula C19H20N2[2] 
Mol. mass 276.376 g/mol
SMILES search in eMolecules, PubChem
Synonyms Incidal, Omeril, diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[3]
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

Not established[4]

Legal status
Routes oral[4]

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries. It is also called Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.[5]

References

  1. ^ Diazoline (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved on 2007-03-02.
  2. ^ Mebhydrolin chemical information (HTML). PubChem. Retrieved on 2007-03-02.
  3. ^ Mebhydroline (HTML). National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved on 2007-03-02.
  4. ^ a b FABAHISTIN 50 mg (Tablets) (HTML). South African Electronic Package Inserts (1970-09). Retrieved on 2007-03-02.
  5. ^ Franks, HM; M. Lawrie, VV Schabinsky, GA Starmer, RK Teo (1981-10-31). Interaction between ethanol and antihistamines: 3. mebhydrolin. (HTML) (English). Med J Aust.. Retrieved on 2007-03-02.
v • d • e
Antihistamines (primarily R06)
Aminoalkyl ethersBromazine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylaminesBrompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediaminesChloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivativesAlimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivativesBuclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic useAntazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical useBamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroidsAntazoline • Azelastine
Other antiallergicsEmedastine • Epinastine • Ketotifen • Olopatadine
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mebhydrolin". A list of authors is available in Wikipedia.
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