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Magaldrate



Magaldrate
Systematic (IUPAC) name
Magnesium aluminate monohydrate
Identifiers
CAS number 1317-26-6
ATC code A02AD02 A02AF01
PubChem 6336542
Chemical data
Formula H3O2-
Mol. mass 86.3092 g/mol
Pharmacokinetic data
Bioavailability Negligible
Metabolism Nil
Half life  ?
Excretion Fecal and renal
Therapeutic considerations
Pregnancy cat.

C

Legal status

OTC

Routes Oral

Magaldrate (INN), is a common antiacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.

Contents

Formula

Al5Mg10(OH)31(SO4)2 H2O

Available forms

Magaldrate is available in the form of oral suspension or tablets.

Interactions and adverse reactions

Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistance. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.

Brand names

The drug is sold with the following brand names:

  • Gradal® (Italy);
  • Magaltop® (Italy);
  • Magralibi® (Italy);
  • Riopan® (Argentina, Austria, Brazil, Germany, Italy).
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Magaldrate". A list of authors is available in Wikipedia.
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