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Lomefloxacin


Lomefloxacin
Systematic (IUPAC) name
1-ethyl-6,8-difluoro- 7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3- carboxylic acid
Identifiers
CAS number	98079-51-7
ATC code	J01MA07 S01AX17
PubChem	3948
DrugBank	APRD01076
Chemical data
Formula	C₁₇H₁₉F₂N₃O₃
Mol. mass	351.348 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	10%
Metabolism	?
Half life	8 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Lomefloxacin hydrochloride (Maxaquin) is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. It is taken orally, usually daily for 10-14 days.

Additional recommended knowledge

Essential Laboratory Skills Guide

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Lomefloxacin is unique in that it forms a magnesium chelate with itself. The chelate is formed between the 2-carbonyl group of two separate lomefloxacin molecules.

v • d • e Antibacterials for systemic use: quinolones (J01M)
Fluoroquinolones	Ciprofloxacin • Enoxacin • Fleroxacin • Gatifloxacin • Gemifloxacin • Grepafloxacin • Levofloxacin • Lomefloxacin • Moxifloxacin • Norfloxacin • Ofloxacin • Pefloxacin • Prulifloxacin • Rufloxacin • Sparfloxacin • Temafloxacin • Trovafloxacin • Sitafloxacin
Other quinolones	Cinoxacin • Flumequine • Nalidixic acid • Oxolinic acid • Pipemidic acid • Piromidic acid • Rosoxacin