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Loewe additivity



 The introduction to this June 2007 provides insufficient context for those unfamiliar with the subject.
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Loewe additivity is one several common reference models used for measuring the effects of drug combinations.

Loewe additivity is based on the idea that an agent should not have synergistic interactions with itself.

References

  • William R Greco, Gregory Bravo, and John Parsons "The Search for Synergy: A Critical Review from a Response Surface Perspective", Pharmacological Reviews 47(2) 331-385 (1995)
  • Loewe and Muischnek. "Effect of combinations: mathematical basis of the problem" Arch. Exp. Pathol. Pharmakol. 114: 313-326, 1926


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Loewe_additivity". A list of authors is available in Wikipedia.
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