List of enzymes

This article is a list of enzymes, sorted by their respective sub-categories and EC number.

See also:

• List of EC numbers
• List of EC numbers (EC 1)
• List of EC numbers (EC 2)
• List of EC numbers (EC 3)
• List of EC numbers (EC 4)
• List of EC numbers (EC 5)
• List of EC numbers (EC 6)

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Category:Oxidoreductases (EC 1) (Oxidoreductase)

• Dehydrogenase
• Luciferase
• DMSO reductase

Category:EC 1.1 (act on the CH-OH group of donors)

• Category:EC 1.1.1 (with NAD⁺ or NADP⁺ as acceptor)
  • Alcohol dehydrogenase (NAD) EC 1.1.1.1
  • Alcohol dehydrogenase (NADP) EC 1.1.1.2
  • Homoserine dehydrogenase EC 1.1.1.3
  • Aminopropanol oxidoreductase EC 1.1.1.4
  • Diacetyl reductase EC 1.1.1.5
  • Glycerol dehydrogenase EC 1.1.1.6
  • Propanediol phosphate dehydrogenase EC 1.1.1.7
  • glycerol-3-phosphate dehydrogenase (NAD) EC 1.1.1.8
  • D-xylulose reductase EC 1.1.1.9
  • L-xylulose reductase EC 1.1.1.10
  • Lactate dehydrogenase EC 1.1.1.27
  • Malate dehydrogenase EC 1.1.1.37
  • Isocitrate dehydrogenase EC 1.1.1.42
  • HMG-CoA reductase EC 1.1.1.88
• Category:EC 1.1.2 (with a cytochrome as acceptor)
• Category:EC 1.1.3 (with oxygen as acceptor)
  • Glucose oxidase EC 1.1.3.4
  • L-gulonolactone oxidase EC 1.1.3.8
  • Xanthine oxidase EC 1.1.3.32
• Category:EC 1.1.4 (with a disulfide as acceptor)
• (with a quinone or similar compound as acceptor)
• Category:EC 1.1.99 (with other acceptors)

Category:EC 1.2 (act on the aldehyde or oxo group of donors)

• Category:EC 1.2.1
  • Acetaldehyde dehydrogenase EC 1.2.1.10
  • Glyceraldehyde 3-phosphate dehydrogenase EC 1.2.1.12
  • Pyruvate dehydrogenase EC 1.2.1.51
• Category:EC 1.2.4
  • Oxoglutarate dehydrogenase EC 1.2.4.2

Category:EC 1.3 (act on the CH-CH group of donors)

• Category:EC 1.3.1 (with NAD⁺ or NADP⁺ as acceptor)
  • Biliverdin reductase EC 1.3.1.24
• (with a cytochrome as acceptor)
• Category:EC 1.3.3 (with oxygen as acceptor)
  • Protoporphyrinogen oxidase EC 1.3.3.4
• (with a quinone or similar compound as acceptor)
• Category:EC 1.3.7 (with an iron-sulfur protein as acceptor)
• Category:EC 1.3.99 (with other acceptors)
  • 5-alpha reductase EC 1.3.99.5

Category:EC 1.4 (act on the CH-NH₂ group of donors)

• Category:EC 1.4.3
  • Monoamine oxidase EC 1.4.3.4

Category:EC 1.5 (act on CH-NH group of donors)

• Category:EC 1.5.1 (with NAD⁺ or NADP⁺ as acceptor)
  • Dihydrofolate reductase EC 1.5.1.3
  • Methylenetetrahydrofolate reductase EC 1.5.1.20
• Category:EC 1.5.3 (with oxygen as acceptor)
  • Sarcosine oxidase EC 1.5.3.1
  • Dihydrobenzophenanthridine oxidase EC 1.5.3.12
• (with a disulfide as acceptor)
• (with a quinone or similar compound as acceptor)
• (with an iron-sulfur protein as acceptor)
• Category:EC 1.5.8 (with a flavin as acceptor)
• Category:EC 1.5.99 (with other acceptors)

Category:EC 1.6 (act on NADH or NADPH)

• Category:EC 1.6.1 (with NAD⁺ or NADP⁺ as acceptor)
• Category:EC 1.6.2 (with a cytochrome as acceptor)
• (with oxygen as acceptor)
• (with a disulfide as acceptor)
• Category:EC 1.6.5 (with a quinone or similar compound as acceptor)
  • NADH dehydrogenase EC 1.6.5.3
• (with a nitrogenous group as acceptor)
• (with an iron-sulfur protein as acceptor)
• (with a flavin as acceptor)
• Category:EC 1.6.99 (with other acceptors)

Category:EC 1.7 (act on other nitrogenous compounds as donors)

• Category:EC 1.7.1 (with NAD⁺ or NADP⁺ as acceptor)
• Category:EC 1.7.2 (with a cytochrome as acceptor)
• Category:EC 1.7.3 (with oxygen as acceptor)
  • Urate oxidase EC 1.7.3.3
• Category:EC 1.7.7 (with an iron-sulfur protein as acceptor)
• Category:EC 1.7.99 (with other acceptors)

Category:EC 1.8 (act on a sulfur group of donors)

• Category:EC 1.8.1 (with NAD⁺ or NADP⁺ as acceptor)
  • Glutathione reductase EC 1.8.1.7
  • Thioredoxin reductase EC 1.8.1.9
• Category:EC 1.8.2 (with a cytochrome as acceptor)
• Category:EC 1.8.3 (with oxygen as acceptor)
  • Sulfite oxidase EC 1.8.3.1
• Category:EC 1.8.4 (with a disulfide as acceptor)
• (with a quinone or similar compound as acceptor)
• (with a sulfur group as acceptor)
• (with an iron-sulfur protein as acceptor)
• (with other, known, acceptors)
• Category:EC 1.8.99 (with other acceptors)

Category:EC 1.9 (act on a heme group of donors)

• Category:EC 1.9.3 (with oxygen as acceptor)
  • Cytochrome c oxidase EC 1.9.3.1
• (with a nitrogenous group as acceptor)

Category:EC 1.97

• Category:EC 1.97.1
  • Deiodinase EC 1.97.1.10
• (with other acceptors)

Category:EC 1.10 (act on diphenols and related substances as donors)

• (with NAD⁺ or NADP⁺ as acceptor)
• Category:EC 1.10.2 (with a cytochrome as acceptor)
  • Coenzyme Q - cytochrome c reductase EC 1.10.2.2
• Category:EC 1.10.3 (with oxygen as acceptor)
  • Catechol oxidase EC 1.10.3.1
  • Laccase EC 1.10.3.2
• (with other acceptors)

Category:EC 1.11 (act on peroxide as an acceptor -- peroxidases)

• Category:EC 1.11.1 (peroxidases)
  • Cytochrome c peroxidase EC 1.11.1.5
  • Catalase EC 1.11.1.6
  • Myeloperoxidase EC 1.11.1.7
  • Thyroid peroxidase EC 1.11.1.8
  • Glutathione peroxidase EC 1.11.1.9

Category:EC 1.12 (act on hydrogen as a donor)

• (with NAD⁺ or NADP⁺ as acceptor)
• (with a cytochrome as acceptor)
• (with a quinone or similar compound as acceptor)
• (with an iron-sulfur protein as acceptor)
• Category:EC 1.12.98 (with other known acceptors)
• (with other acceptors)

Category:EC 1.13 (act on single donors with incorporation of molecular oxygen)

• Category:EC 1.13.11 (With incorporation of two atoms of oxygen)
  • 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)
• Category:EC 1.13.12 (With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases))
  • Renilla luciferase EC 1.13.12.5
  • Cypridina luciferase EC 1.13.12.6
  • Firefly luciferase EC 1.13.12.7
  • Watasenia luciferase EC 1.13.12.8
  • Oplophorus luciferase EC 1.13.12.13

Category:EC 1.14 (act on paired donors with incorporation of molecular oxygen)

• Cytochrome P450 oxidase
• Category:Cytochrome P450
  • Aromatase EC 1.14.14.1
  • CYP2D6 EC 1.14.14.1
  • CYP2E1 EC 1.14.14.1
  • CYP3A4 EC 1.14.14.1
  • Cytochrome P450 oxidase
• Category:EC 1.14.12
  • Nitric oxide dioxygenase
• Category:EC 1.14.13
  • Nitric oxide synthase EC 1.14.13.39
• Category:EC 1.14.14
  • Aromatase EC 1.14.14.1
  • CYP2D6 EC 1.14.14.1
  • CYP2E1 EC 1.14.14.1
  • CYP3A4 EC 1.14.14.1
• Category:EC 1.14.16
  • Phenylalanine hydroxylase EC 1.14.16.1
• Category:EC 1.14.18
  • Tyrosinase EC 1.14.18.1

Category:EC 1.15 (act on superoxide radicals as acceptors)

• Category:EC 1.15.1
  • Superoxide dismutase EC 1.15.1.1

Category:EC 1.16 (oxidize metal ions)

• Category:EC 1.16.3
  • Ceruloplasmin EC 1.16.3.1

Category:EC 1.17 (act on CH or CH₂ groups)

Category:EC 1.18 (act on iron-sulfur proteins as donors)

• Category:EC 1.18.6
  • Nitrogenase EC 1.18.6.1

(act on reduced flavodoxin as donor)

(act on phosphorus or arsenic as donors)

Category:EC 1.21 (act on X-H and Y-H to form an X-Y bond)

Category:EC 1.97 (other oxidoreductases)

Category:Transferases (EC 2) (Transferase)

• Glutathione S-transferase

Category:EC 2.1 (transfer one-carbon groups, Methylase)

• Category:EC 2.1.1
  • Catechol-O-methyl transferase EC 2.1.1.6
  • DNA methyltransferase EC 2.1.1.72, EC 2.1.1.113, EC 2.1.1.37
  • Histone methyltransferase EC 2.1.1.43, EC 2.1.1.125
• Category:EC 2.1.3
  • ATCase EC 2.1.3.2
  • Ornithine transcarbamoylase EC 2.1.3.3

(transfer aldehyde or ketone groups)

Category:EC 2.3 (acyltransferases)

• Category:EC 2.3.1
  • Aminolevulinic acid synthase EC 2.3.1.37
  • Choline acetyltransferase EC 2.3.1.6
• Category:EC 2.3.2
  • Factor XIII EC 2.3.2.13
  • Gamma glutamyl transpeptidase EC 2.3.2.2
  • Transglutaminase EC 2.3.2.13

Category:EC 2.4 (glycosyltransferases)

• Category:EC 2.4.2
  • Hypoxanthine-guanine phosphoribosyltransferase EC 2.4.2.8

Category:EC 2.5

• Category:EC 2.5.1
  • Thiaminase EC 2.5.1.2

Category:EC 2.5 (transfer alkyl or aryl groups, other than methyl groups)

Category:EC 2.6 (transfer nitrogenous groups)

• Category:EC 2.6.1
  • Alanine transaminase EC 2.6.1.2
  • Aspartate transaminase EC 2.6.1.1

Category:EC 2.8 (transfer sulfur-containing groups)

(transfer selenium-containing groups)

Category:Hydrolases (EC 3) (Hydrolase)

• Hydrolytic enzyme

Category:EC 3.1 (act on ester bonds)

• Nuclease
• Endonuclease
• Exonuclease
• Category:EC 3.1.1
  • Acid hydrolase
  • Phospholipase A (EC 3.1.1.4)
  • Acetylcholinesterase (EC 3.1.1.7)
  • Cholinesterase (EC 3.1.1.8)
  • Lipoprotein lipase (EC 3.1.1.34)
• Category:EC 3.1.2
  • Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15)
• Category:EC 3.1.3
  • Phosphatase
  • Alkaline phosphatase (EC 3.1.3.1)
  • Fructose bisphosphatase (EC 3.1.3.11)
• Category:EC 3.1.4
  • Phospholipase C (EC 3.1.4.3)
  • CGMP specific phosphodiesterase type 5 (EC 3.1.4.17)
  • Phospholipase D (EC 3.1.4.50)
• Category:EC 3.1.21
  • Restriction enzyme Type 1 (EC 3.1.21.3)
  • Deoxyribonuclease I (EC 3.1.21.1)
• Category:EC 3.1.26
  • RNase H (EC 3.1.26.4)
• Category:EC 3.1.27
  • Ribonuclease

Category:EC 3.2 (act on sugars - glycosylases)

• Category:EC 3.2.1
  • Amylase (EC 3.2.1.1)
  • Sucrase (EC 3.2.1.10)
  • Chitinase (EC 3.2.1.14)
  • Lysozyme (EC 3.2.1.17)
  • Maltase (EC 3.2.1.20)
  • Lactase (EC 3.2.1.23)
  • Beta-galactosidase (EC 3.2.1.23)
  • Hyaluronidase (EC 3.2.1.35)

Category:EC 3.3 (act on ether bonds)

Category:EC 3.4 (act on peptide bonds - Peptidase)

• Category:EC 3.4.11
  • Alanine aminopeptidase
• Category:EC 3.4.15
  • [[Angiotensin-converting
• Category:EC 3.4.21
  • Serine protease
  • Chymotrypsin (EC 3.4.21.1)
  • Trypsin (EC 3.4.21.4)
  • Thrombin (EC 3.4.21.5)
  • Factor X (EC 3.4.21.6)
  • Plasmin (EC 3.4.21.7)
  • Acrosin (EC 3.4.21.10)
  • Factor VII (EC 3.4.21.21)
  • Factor IX (EC 3.4.21.22)
  • Factor XI (EC 3.4.21.27)
  • Elastase (EC 3.4.21.37)
  • Factor XII (EC 3.4.21.38)
  • Tissue plasminogen activator (EC 3.4.21.68)
  • Protein C (EC 3.4.21.69)
• Category:EC 3.4.22
  • Separase (EC 3.4.22.49)
• Category:EC 3.4.23
  • Pepsin (EC 3.4.23.1)
  • Rennet (EC 3.4.23.4)
  • Renin (EC 3.4.23.15)
  • Trypsinogen (EC 3.4.23.18) and (20/21/23/24/26)
  • Plasmepsin (EC 3.4.23.39)
• Category:EC 3.4.24
  • Matrix metalloproteinase (EC 3.4.24.7)
• • Metalloendopeptidase

Category:EC 3.5 (act on carbon-nitrogen bonds, other than peptide bonds)

• Category:EC 3.5.1 (In linear amides)
  • Urease (EC 3.5.1.5)
• Category:EC 3.5.2 (In cyclic amides)
  • Beta-lactamase (EC 3.5.2.6)
• Category:EC 3.5.3 (In linear amidines)
  • Arginase (EC 3.5.3.1)
• Category:EC 3.5.4 (In cyclic amidines)
  • Adenosine deaminase (EC 3.5.4.4)
  • GTP cyclohydrolase I (EC 3.5.4.16)
• Category:EC 3.5.5 (In nitriles)
  • Nitrilase (EC 3.5.5.1)

Category:EC 3.6 (act on acid anhydrides)

• Category:EC 3.6.1
  • Helicase
  • DnaB helicase
  • RecQ helicase
• Category:EC 3.6.3
  • ATPase
  • NaKATPase (EC 3.6.3.9)
  • ATP synthase (EC 3.6.3.14)

Category:EC 3.7 (act on carbon-carbon bonds)

• Kynureninase EC 3.7.1.3

Category:EC 3.8 (act on halide bonds)

(act on phosphorus-nitrogen bonds)

(act on sulfur-nitrogen bonds)

Category:EC 3.11 (act on carbon-phosphorus bonds)

(act on sulfur-sulfur bonds)

(act on carbon-sulfur bonds)

Category:Lyases (EC 4) (Lyase)

Category:EC 4.1 (carbon-carbon lyases)

• Category:EC 4.1.1
  • Ornithine decarboxylase (EC 4.1.1.17)
  • Uridine monophosphate synthetase (EC 4.1.1.23)
  • Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28)
  • RubisCO (EC 4.1.1.39)

Category:EC 4.2 (carbon-oxygen lyases)

• Category:EC 4.2.1
  • Carbonic anhydrase (EC 4.2.1.1)
  • Tryptophan synthase (EC 4.2.1.20)

Category:EC 4.3 (carbon-nitrogen lyases)

Category:EC 4.4 (carbon-sulfur lyases)

Category:EC 4.5 (carbon-halide lyases)

Category:EC 4.6 (phosphorus-oxygen lyases)

• Category:EC 4.6.1
  • Adenylate cyclase (EC 4.6.1.1)
  • Guanylate cyclase (EC 4.6.1.2)

Category:Isomerases (EC 5) (Isomerase)

Category:EC 5.1 (racemases and epimerases)

Category:EC 5.2 (cis-trans-isomerases)

Category:EC 5.3 (intramolecular oxidoreductases)

• Category:EC 5.3.3
  • Enoyl CoA isomerase (EC 5.3.3.8)
• Category:EC 5.3.4
  • Protein disulfide isomerase (EC 5.3.4.1)

Category:EC 5.4 (intramolecular transferases -- mutases)

• Category:EC 5.4.2
  • Phosphoglucomutase (EC 5.4.2.2)

(intramolecular lyases)

Category:EC 5.99 (other isomerases)

• Category:EC 5.99.1
  • Topoisomerase (type I: EC 5.99.1.2, type II: EC 5.99.1.3)

Category:Ligases (EC 6) (Ligase)

Category:EC 6.1 (form carbon-oxygen bonds)

Category:EC 6.2 (form carbon-sulfur bonds)

Category:EC 6.3 (form carbon-nitrogen bonds)

• Glutamine synthetase (EC 6.3.1.2)
• Argininosuccinate synthetase (EC 6.3.4.5)
• CTP synthase (EC 6.3.4.2)

Category:EC 6.4 (form carbon-carbon bonds)

• Pyruvate carboxylase (EC 6.4.1.1)
• Acetyl-CoA carboxylase (EC 6.4.1.2)

Category:EC 6.5 (form phosphoric ester bonds)

DNA ligase (EC 6.5.1.1)

Category:EC 6.6 (form nitrogen-metal bonds)