List of benzodiazepines

The various benzodiazepines and their respective trade-names, half-lives, and primary uses are listed in the following table.

Drug Name	Common Brand Names*	Time to Peak (Onset of action in hours)	Elimination Half-Life (h) [active metabolite]**	Primary Effects	Approximate Equivalent Dose***
Alprazolam	Xanax, Xanor, Tafil, Alprox, Frontal(Brazil)	1-2	6-12 hours	anxiolytic	0.5 mg
Bromazepam	Lexotanil, Lexotan, Lexomil, Somalium, Bromam	1-3	10-20 hours	anxiolytic	5-6 mg
Chlordiazepoxide	Librium, Tropium, Risolid, Klopoxid	1.5-4	5-30 hours [36-200 hours]	anxiolytic	25 mg
Cinolazepam	Gerodorm	?	9 h	sedative	40 mg
Clonazepam	Klonopin, Klonapin, Rivotril	1-4	18-50 hours	anxiolytic, anticonvulsant	0.5 mg
Cloxazolam	Olcadil (Brazil)	2-5 (?)	18-50 hours	anxiolytic, anticonvulsant	1 mg
Clorazepate	Tranxene	Variable	[36-100 hours]	anxiolytic, anticonvulsant	15 mg
Diazepam	Valium, Apzepam, Stesolid, Vival, Apozepam, Hexalid, Valaxona	1-2	20-100 hours [36-200]	anxiolytic, anticonvulsant, muscle relaxant	10 mg
Estazolam	ProSom	.5-5	10-24 h	hypnotic	1-2 mg
Flunitrazepam	Rohypnol, Fluscand, Flunipam, Ronal, Rohydorm (Brazil)	.5-3	18-26 hours [36-200 hours]	hypnotic	1 mg
Flurazepam	Dalmadorm, Dalmane	1-1.5	[40-250 hours]	hypnotic	25 mg
Halazepam	Paxipam	1-3	[30-100 hours]	anxiolytic	20-40 mg
Ketazolam	Anxon	2.5-3	30-100 hours [36-200]	anxiolytic	15-30 mg
Loprazolam	Dormonoct	2-4	6-12 hours	hypnotic	1-2 mg
Lorazepam	Ativan, Temesta, Lorabenz	2-4	10-20 hours	anxiolytic,anticonvulsant	1 mg
Lormetazepam	Loramet, Noctamid, Pronoctan	.5-2	10-12 hours	hypnotic	1-2 mg
Medazepam	Nobrium	?	36-200 hours	anxiolytic	10 mg
Midazolam	Dormicum, Versed, Hypnovel, Dormonid (Brazil)	.5-1	3 hours (1.8-6 hours)	hypnotic	5-15 mg
Nitrazepam	Mogadon, Alodorm, Pacisyn, Dumolid	.5-7	15-38 hours	hypnotic	10 mg
Nordazepam	Madar, Stilny	?	50-120 hours	anxiolytic	10 mg
Oxazepam	Seresta, Serax, Serenid, Serepax, Sobril, Oxascand, Alopam, Oxabenz, Oxapax	3-4	4-15 hours	anxiolytic	25-30 mg
Phenazepam
Pinazepam	Domar	?	40-100 hours	anxiolytic	5-20 mg
Prazepam	Centrax	2-6	36-200 hours	anxiolytic	10-20 mg
Quazepam	Doral	1-5	39-120 hours	hypnotic	20 mg
Temazepam	Restoril, Normison, Euhypnos	.5-3	8-22 hours	hypnotic	20 mg
Tetrazepam	Mylostan	1-3	3-26 hours	Skeletal muscle relaxant	50mg
Triazolam	Halcion, Rilamir	.5-2	2 hours	hypnotic	0.25 mg

Atypical benzodiazepine receptor ligands

Drug Name	Common Brand Names*	Elimination Half-Life (h) [active metabolite]**	Primary Effects	Approximate Equivalent Dose***
Clobazam	Frisium, Urbanol	8-60 hours	anxiolytic, anticonvulsant	N/A, typical dose 5-20 mg
DMCM	?	?	anxiogenic, convulsant	N/A, not used therapeutically
Flumazenil	Anexate, Lanexat, Mazicon, Romazicon	1 hour	antidote	N/A, typical dose 0.2 - 0.6 mg

Additional recommended knowledge

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Essential Laboratory Skills Guide

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*Not all trade names are listed. Click on drug name to see a more comprehensive list.
**The duration of apparent action is usually considerably less than the half-life. With most benzodiazepines, noticeable effects usually wear off within a few hours. Nevertheless, as long as the drug is present it will exert subtle effects within the body. These effects may become apparent during continued use or may appear as withdrawal symptoms when dosage is reduced or the drug is stopped.
***Equivalent doses are based on clinical experience but may vary between individuals.[1]

References

[2] [3]

Category: Benzodiazepines

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "List_of_benzodiazepines". A list of authors is available in Wikipedia.