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Latanoprost



Latanoprost
Systematic (IUPAC) name
propan-2-yl 7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pentyl) -cyclopentyl] hept-5-enoate
Identifiers
CAS number	130209-82-4
ATC code	S01EE01
PubChem	60798
DrugBank	APRD01065
Chemical data
Formula	C₂₆H₄₀O₅
Mol. mass	432.593 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	17 minutes
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Topical (eye drops)

Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.

Additional recommended knowledge

Essential Laboratory Skills Guide

Safe Weighing Range Ensures Accurate Results

What is the Correct Way to Check Repeatability in Balances?

It is also known by the brand name of Xalatan manufactured by Pfizer.

Side effects

Possible side effects:

May cause reddening of the eyes (hyperemia)
May cause blurred vision;
May cause eyelid redness;
May permanently darken eyelashes;
May cause eye discomfort;
May eventually cause permanent darkening of the iris to brown (heterochromia);
May cause a temporary burning sensation during use.
May cause thickening of the eyelashes.
Rarely, herpes simplex keratitis.

v • d • e Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics	Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine
Parasympathomimetics	Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine
Carbonic anhydrase inhibitors	Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide
Beta blocking agents	Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol
Prostaglandin analogues	Bimatoprost • Latanoprost • Travoprost • Unoprostone
Other agents	Dapiprazole • Guanethidine

v • d • e Eicosanoids: prostaglandins
Endogenous/series 2	D₂ - E₂ (Dinoprostone) - H₂ - I₂ (Prostacyclin)
Prostaglandin analogues	Alprostadil - Beraprost - Bimatoprost - Carboprost - Enprostil - Iloprost - Latanoprost - Misoprostol - Travoprost - Treprostinil